4231-84-9Relevant articles and documents
Synthetic autocatalysts show organocatalysis of other reactions
Kamioka, Seiji,Ajami, Dariush,Rebek Jr., Julius
, p. 7324 - 7326 (2009)
A molecule capable of both autocatalysis and organocatalysis was synthesized. The autocatalytic activity results from the self-complementary recognition sites provided by hydrogen bonding between heterocyclic subunits and the organocatalysis resides in an embedded thiourea function. The behavior of the molecule suggests both replication and metabolism can be engineered into synthetic compounds.
Desulfurative Chlorination of Alkyl Phenyl Sulfides
Canestrari, Daniele,Lancianesi, Stefano,Badiola, Eider,Strinna, Chiara,Ibrahim, Hasim,Adamo, Mauro F. A.
supporting information, p. 918 - 921 (2017/02/26)
The chlorination of readily available secondary and tertiary alkyl phenyl sulfides using (dichloroiodo)benzene (PhICl2) is reported. This mild and rapid nucleophilic chlorination is extended to sulfa-Michael derived sulfides, affording elimination-sensitive β-chloro carbonyl and nitro compounds in good yields. The chlorination of enantioenriched benzylic sulfides to the corresponding inverted chlorides proceeds with high stereospecificity, thus providing a formal entry into enantioenriched chloro-Michael adducts. A mechanism implying the formation of a dichloro-λ4-sulfurane intermediate is proposed.
Conjugate addition nitro-Mannich reaction of carbon and heteroatom nucleophiles to nitroalkenes
Anderson, James C.,Kalogirou, Andreas S.,Tizzard, Graham J.
, p. 9337 - 9351 (2015/03/05)
The conjugate addition nitro-Mannich reactions of ethyl-β-nitroacrylate (1) and β-nitrostyrene (2) with electron rich aromatic nucleophiles, stabilized carbanions, alcohols, amines, thiols, and diphenyl phosphine oxide were investigated. The one pot conju
