42503-30-0Relevant articles and documents
Electrochemically Mediated Direct C(sp3)?H Sulfonylation of Xanthene Derivatives
Feng, Yu-Feng,Gao, Lei,Ma, Xian-Li,Mo, Zu-Yu,Pan, Ying-Ming,Tang, Hai-Tao,Wei, Wan-Jie,Zhong, Yu-Jing
supporting information, (2022/01/06)
The construction of C(sp3)-sulfonyl bonds through direct sulfonylation of C(sp3)?H bond presents a number of challenges, so an electrochemical oxidation-induced direct sulfonylation of the xanthene C(sp3)?H bond was developed. Significant advantages of this method are high atom efficiency, functional group tolerance, transition metal- and oxidant-free conditions. The in vitro cytotoxicity of all product is evaluated by MTT assay against human cancer cell lines. The results reveal that most of the compounds 3 da and 3 af have good inhibitory activity on tumor cell lines. (Figure presented.).