42718-55-8 Usage
Description
(S)-N-CARBOBENZOXYL-N,N-DIMETHYL-L-PROLINAMIDE, a chemical compound with the molecular formula C15H19NO3, is a proline-derived compound that plays a significant role in organic synthesis and chemical reactions. It is widely recognized for its utility as a chiral auxiliary in the asymmetric synthesis of various organic molecules, where it contributes to the control of stereoselectivity. (S)-N-CARBOBENZOXYL-N,N-DIMETHYL-L-PROLINAMIDE also serves as a ligand in metal-catalyzed reactions and as a substrate in enzymatic reactions, further highlighting its versatility in the field of chemistry.
Uses
Used in Organic Synthesis:
(S)-N-CARBOBENZOXYL-N,N-DIMETHYL-L-PROLINAMIDE is used as a chiral auxiliary for enhancing the stereoselectivity of asymmetric synthesis in organic chemistry. Its proline-based structure allows for selective reactions, making it a valuable tool in the creation of complex organic molecules with desired stereochemistry.
Used in Pharmaceutical and Medicinal Chemistry:
In the pharmaceutical and medicinal chemistry industry, (S)-N-CARBOBENZOXYL-N,N-DIMETHYL-L-PROLINAMIDE is used as a key component in the development of drug molecules. Its ability to influence chirality and stereochemistry is crucial for the synthesis of biologically active compounds with improved efficacy and selectivity.
Used in Metal-Catalyzed Reactions:
(S)-N-CARBOBENZOXYL-N,N-DIMETHYL-L-PROLINAMIDE acts as a ligand in metal-catalyzed reactions, where it aids in the selective formation of desired products. This application is particularly important in the synthesis of complex molecules and the development of new catalytic processes.
Used in Enzymatic Reactions:
As a substrate in enzymatic reactions, (S)-N-CARBOBENZOXYL-N,N-DIMETHYL-L-PROLINAMIDE contributes to the study and understanding of enzyme mechanisms and the development of biocatalytic processes. Its role in these reactions can lead to the discovery of new enzymes or the improvement of existing ones for industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 42718-55-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,7,1 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 42718-55:
(7*4)+(6*2)+(5*7)+(4*1)+(3*8)+(2*5)+(1*5)=118
118 % 10 = 8
So 42718-55-8 is a valid CAS Registry Number.
42718-55-8Relevant articles and documents
Amidation reaction of carboxylic acid with formamide derivative using SO3?pyridine
Kawano, Shota,Saito, Kodai,Yamada, Tohru
supporting information, p. 584 - 586 (2018/04/12)
The amidation reaction of carboxylic acid derivatives was developed using sulfur trioxide pyridine complex (SO3?py) as a commercially available and easily handled oxidant. This method could be applied to the reaction of various aromatic and aliphatic carboxylic acids, including optically active ones, with formamide derivatives to afford the corresponding amides in good to high yields.
Small organic molecule catalyzed enantioselective direct aldol reaction in water
Chimni, Swapandeep Singh,Mahajan, Dinesh
, p. 2108 - 2119 (2007/10/03)
Protonated pyrrolidine based small organic molecules have been designed and evaluated for the asymmetric direct aldol reaction in water. The designed organocatalysts are multifunctional in nature and exploit the combined effect of hydrogen bonding and hydrophobic interactions for enantioselective catalysis in water. As a result a unique direct asymmetric aldol reaction in water catalyzed by a small organic molecule having an amide linkage has been developed. The developed catalyst affords chiral β-hydroxyketones in good yields (93%) and enantioselectivities (upto 62%) in water.
