428854-21-1

Basic information

• Product Name: 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5-diamine
• Synonyms: 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5-diamine
• CAS NO: 428854-21-1
• Molecular Weight: 335.343
• Mol File: 428854-21-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5-diamine(428854-21-1)
• EPA Substance Registry System: 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5-diamine(428854-21-1)

Safety Data

• Hazardous Substances Data: 428854-21-1(Hazardous Substances Data)

Downstream Products

• 1361570-16-2 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-7-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]-7,9-dihydro-8H-purin-8-one 
• 1361570-83-3 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-N⁵-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]pyrimidine-4,5-diamine 
• 1361569-79-0 7-(1-cyclopropylpiperidin-4-yl)-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-7,9-dihydro-8H-purin-8-one 
• 1361570-30-0 N⁵-(1-cyclopropylpiperidin-4-yl)-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5-diamine 

Relevant articles and documents

Novel sulfonamide-substituted pyrazolopyridine derivatives

The invention relates to novel pyrazolopyridine derivatives of formula (I) wherein R1 represents H, Cl or NH2, and R2 and R3 form; together with the heteroatoms to which they are bonded, a five to six-membered heterocycle which can be saturated or partially unsaturated, can optionally contain at least one other heteroatom from the group N, O, S and can be optionally substituted. The invention also relates to salts, isomers and hydrates of said derivatives, in the form of stimulators of soluble guanylate cyclase and as agents for treating cardiovascular diseases, hypertonia, thrombo-embolic diseases and ischaemia, sexual dysfunction, inflammations, and diseases of the central nervous system.