431-37-8

Basic information

• Product Name: 1-CHLORO-3,3,3-TRIFLUOROACETONE
• Synonyms: 3-CHLORO-1,1,1-TRIFLUOROACETONE;1-CHLORO-3,3,3-TRIFLUOROACETONE;1-Chloro-3,3,3-trifluoroacetone,97%;1-Chloro-3,3,3-trifluoro-2-propanone;3-Chloro-1,1,1-trifluoropropan-2-one, 3-Chloro-2-oxo-1,1,1-trifluoropropane;3-Chloro-1,1,1-trifluoro-2-propanone;2-Propanone,3-chloro-1,1,1-trifluoro-
• CAS NO: 431-37-8
• Molecular Formula: C₃H₂ClF₃O
• Molecular Weight: 146.5
• Mol File: 431-37-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 71-72°C
• Appearance: /
• Density: 1,45 g/cm3
• Vapor Pressure: 125mmHg at 25°C
• Refractive Index: 1.3445
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1-CHLORO-3,3,3-TRIFLUOROACETONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CHLORO-3,3,3-TRIFLUOROACETONE(431-37-8)
• EPA Substance Registry System: 1-CHLORO-3,3,3-TRIFLUOROACETONE(431-37-8)

Safety Data

• Hazard Codes: F,T
• Statements: 10-20/21/22-36/37/38
• Safety Statements: 16-23-26-36
• RIDADR: 1993
• Hazardous Substances Data: 431-37-8(Hazardous Substances Data)

Usage

Description

1-Chloro-3,3,3-trifluoroacetone is an organic compound that serves as a versatile intermediate in the synthesis of various organic and pharmaceutical compounds. It is characterized by its unique chemical structure, which features a chloro group and three fluoro groups attached to a carbonyl group. This structure endows it with specific reactivity and properties that make it valuable in chemical and pharmaceutical applications.

Uses

1. Used in Organic Synthesis:
1-Chloro-3,3,3-trifluoroacetone is used as an organic synthesis intermediate for the production of various organic compounds. Its unique structure allows for selective reactions and functional group transformations, making it a valuable building block in the synthesis of complex organic molecules.
2. Used in Pharmaceutical Synthesis:
1-Chloro-3,3,3-trifluoroacetone is also used as a pharmaceutical intermediate, playing a crucial role in the development of new drugs and pharmaceutical compounds. Its reactivity and structural properties enable the creation of novel drug candidates with potential therapeutic applications.
3. Used in Laboratory Research and Development:
In the field of laboratory research and development, 1-chloro-3,3,3-trifluoroacetone is employed as a key compound for exploring new reaction pathways and developing innovative synthetic methods. Its unique properties make it an attractive candidate for studying various chemical reactions and mechanisms.
4. Used in Chemical Production Process:
1-Chloro-3,3,3-trifluoroacetone is utilized in the chemical production process, where it serves as a starting material or intermediate for the synthesis of various chemicals and materials. Its versatility and reactivity contribute to the development of new products and the improvement of existing chemical processes.

InChI:InChI=1/C3H2ClF3O/c4-1-2(8)3(5,6)7/h1H2

Upstream product

• 382-96-7 (2-chloro-1-trifluoromethyl-vinyl)-methyl ether 
• 363-58-6 ethyl 2-chloro-4,4,4-trifluoro-3-oxobutanoate 
• 126266-75-9 3,3-dichloro-1,1,1-trifluoroacetone 

Downstream Products

• 430-51-3 1-fluoro-2-propanone 
• 431-05-0 1,1-difluoroacetone 
• 421-50-1 1,1,1-trifluoro-2-propanone 
• 67-64-1 acetone 
• 109113-97-5 6-chloro-2-trifluoromethylimidazo<1,2-b>pyridazine 
• 365427-38-9 3-methoxy-N-(3,3,3-trifluoro-2-oxopropyl)benzamide 
• 34509-08-5 3-(Butylthio)-1,1,1-trifluoropropan-2-one 
• 349-49-5 4-(trifluoromethyl)-1,3-thiazol-2-amine 

Relevant articles and documents

-

-