433-48-7 Usage
Description
3-Fluoropyruvate, also known as 3-fluoropyruvic acid, is a pyruvic acid derivative with a 3-fluoro substituent. It is a significant compound in the field of chemistry and biochemistry due to its unique properties and potential applications.
Uses
Used in Chemical Synthesis:
3-Fluoropyruvate is used as a building block for the synthesis of various organic compounds. Its unique fluoro substituent allows for the creation of a wide range of molecules with different properties and applications.
Used in Pharmaceutical Industry:
3-Fluoropyruvate is used as a mechanistic agent for the inactivation of mandelate racemase, an enzyme involved in the bacterial degradation of aromatic compounds. This property makes it a potential candidate for the development of new antibiotics or other therapeutic agents targeting bacterial infections.
Used in Biochemical Research:
3-Fluoropyruvate is used as a research tool to study the effects of fluorination on the structure and function of pyruvic acid and its derivatives. This can provide valuable insights into the role of fluorine in biological systems and help in the design of new drugs and bioactive molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 433-48-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,3 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 433-48:
(5*4)+(4*3)+(3*3)+(2*4)+(1*8)=57
57 % 10 = 7
So 433-48-7 is a valid CAS Registry Number.
InChI:InChI=1/C3H3FO3/c4-1-2(5)3(6)7/h1H2,(H,6,7)/p-1
433-48-7Relevant articles and documents
Kinetic resolution of 3-fluoroalanine using a fusion protein of D-amino acid oxidase with Vitroscilla hemoglobin
Seo, Young-Man,Khang, Yong-Ho,Yun, Hyungdon
body text, p. 820 - 822 (2011/11/30)
In this study, a fusion protein (VHb-DAAO) of D-amino acid oxidase (DAAO) with Vitreoscilla hemoglobin (VHb) was functionally expressed in Escherichia coli and purified. The kcat value VHb-DAAO (47.1 s-1) towards rac-3-flouroalanine was about 2-fold higher than that of DAAO (21.9 s -1). rac-3-Flouroalanine (500 mm) was kinetically resolved into (R)-3-fluoroalanine with high enatiomeric excess (>99%) by VHb-DAAO with about 52% conversion.
Stereoselectivities in Enzymatic Syntheses of Fluorocitric Acid
Brandaenge, Svante,Dahlman, Olof,Mahlen, Anders,Moerch, Lars
, p. 67 - 70 (2007/10/02)
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