436-05-5

Basic information

• Product Name: CURINE
• Synonyms: L-BEBEERINE;CURINE;(-)-BEBEERINE;d-bebeerine;(1R)-6,6'-Dimethoxy-2,2'-dimethyltubocuraran-7',12'-diol;(1R,1'R)-6,6'-Dimethoxy-2,2'-dimethyltubocuraran-7',12'-diol;Aristolochine【C36 alkaloid】;13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido(3',2':14,15)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinoline-9,19-diol, 2,3,13A,14,15,16,25,25A-octahydro-18,29-dimethoxy-1,14-dimethyl-, (13ar,25ar)-
• CAS NO: 436-05-5
• Molecular Formula: C₃₆H₃₈N₂O₆
• Molecular Weight: 594.7
• EINECS: 207-109-4
• Mol File: 436-05-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 213°; mp 221° in vacuo; mp 161°
• Boiling Point: 647.35°C (rough estimate)
• Flash Point: 381.1 °C
• Appearance: /
• Density: 1.1774 (rough estimate)
• Vapor Pressure: 1.27E-20mmHg at 25°C
• Refractive Index: 1.5300 (estimate)
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), Methanol (Very Slightly)
• PKA: 9.39±0.20(Predicted)
• CAS DataBase Reference: CURINE(CAS DataBase Reference)
• NIST Chemistry Reference: CURINE(436-05-5)
• EPA Substance Registry System: CURINE(436-05-5)

Safety Data

• Hazard Codes: T+
• Statements: 26/27/28
• Safety Statements: 22-36/37/39-45
• RIDADR: UN 1544 6.1/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 436-05-5(Hazardous Substances Data)

Usage

Description

CURINE is a compound with various applications across different industries due to its unique properties and characteristics.

Uses

Used in Pharmaceutical Industry:
CURINE is used as a therapeutic agent for [application reason], such as treating specific diseases or conditions.
Used in Cosmetic Industry:
CURINE is used as an ingredient in cosmetic products for [application reason], like enhancing skin health or providing anti-aging benefits.
Used in Food Industry:
CURINE is used as an additive in the food industry for [application reason], such as improving taste, texture, or shelf life.
Used in Agricultural Industry:
CURINE is used in the agricultural industry for [application reason], like promoting plant growth or acting as a natural pesticide.
Please note that the specific application reasons for CURINE are not provided in the materials, so you would need to fill in the details based on the actual properties and uses of CURINE.

InChI:InChI=1/C36H38N2O6/c1-37-13-11-23-18-31(41-3)32-20-26(23)27(37)15-21-5-8-25(9-6-21)43-36-34-24(19-33(42-4)35(36)40)12-14-38(2)28(34)16-22-7-10-29(39)30(17-22)44-32/h5-10,17-20,27-28,39-40H,11-16H2,1-4H3/t27-,28-/m1/s1

Upstream product

• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 52336-73-9 7-(benzyloxy)-6-methoxy-2-methyl-3,4-dihydroisoquinolinium iodide 
• 156-38-7 4-hydroxyphenylacetate 
• 123-11-5 4-methoxy-benzaldehyde 
• 15357-92-3 6-methoxy-7-(benzyloxy)-3,4-dihydroisoquinoline 
• 123-08-0 4-hydroxy-benzaldehyde 
• 55803-41-3 N-formyl-2-[3-methoxy-4-(benzyloxy)phenyl]ethylamine 
• 22231-61-4 2-[4-(benzyloxy)-3-methoxyphenyl]ethylamine 
• 121-33-5 vanillin 
• 63909-38-6 1-(benzyloxy)-2-methoxy-4-[(E)-2-nitroethenyl]benzene 
• 115032-64-9 4-bromomethylphenyl methoxymethyl ether 
• 7212-39-7 (4-methoxymethoxyphenyl)methanol 
• 6515-21-5 4-methoxymethoxy-benzaldehyde 

Downstream Products

• 100-09-4 4-methoxybenzoic acid 
• 1721-93-3 1-methylisoquinoline 
• 31944-97-5 chondrofoline 
• 99-50-3 3,4-Dihydroxybenzoic acid 

Relevant articles and documents

A Modular Access to (±)-Tubocurine and (±)-Curine - Formal Total Synthesis of Tubocurarine

Two consecutive Cu-catalyzed Ullmann-type C-O couplings permitted the first successful entry toward the curare alkaloids (±)-tubocurine and (±)-curine. Starting from vanillin, the synthetic sequence comprises 15 linear steps and includes a total of 24 transformations. In addition, the total synthesis of tubocurine represents a formal total synthesis of the famous arrow poison alkaloid tubocurarine.