436-40-8

Basic information

• Product Name: Inproquone
• Synonyms: Inproquone;Bayer E-39;E 39;E-39;NSC-17261;RP 6870;2,5-bis(aziridin-1-yl)-3,6-dipropoxy-cyclohexa-2,5-diene-1,4-dione;2,5-bis(aziridin-1-yl)-3,6-dipropoxycyclohexa-2,5-diene-1,4-dione
• CAS NO: 436-40-8
• Molecular Formula: C16H22N2O4
• Molecular Weight: 306.36
• Mol File: 436-40-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 103.75°C
• Boiling Point: 446.97°C (rough estimate)
• Flash Point: 235.8°C
• Appearance: /
• Density: 1.1118 (rough estimate)
• Vapor Pressure: 7.14E-09mmHg at 25°C
• Refractive Index: 1.5800 (estimate)
• PKA: -0.18±0.20(Predicted)
• CAS DataBase Reference: Inproquone(CAS DataBase Reference)
• NIST Chemistry Reference: Inproquone(436-40-8)
• EPA Substance Registry System: Inproquone(436-40-8)

Safety Data

• Hazardous Substances Data: 436-40-8(Hazardous Substances Data)

Usage

General Description

Inproquone is an organic compound that belongs to the quinolinone class of chemicals. Its chemical structure consists of a quinoline ring system with a ketone group and a propyl substitution at the 2-position, as well as an aromatic system. Inproquone is known for its potential antimalarial properties and has been studied as a potential drug candidate for the treatment of malaria. It is believed to act by targeting the hemozoin formation pathway, a key process in the survival and replication of the malaria parasite within the human body. Research into the pharmacological and biological properties of inproquone is ongoing, with the goal of developing new and effective antimalarial treatments.

InChI:InChI=1/C16H22N2O4/c1-3-9-21-15-11(17-5-6-17)14(20)16(22-10-4-2)12(13(15)19)18-7-8-18/h3-10H2,1-2H3

Upstream product

• 7251-14-1 2,5-bis-aziridin-1-yl-3,6-dichloro-[1,4]benzoquinone 
• 6819-41-6 sodium n-propoxide 
• 118-75-2 chloranil 
• 488-48-2 tetrabromobenzoquinone 
• 57998-73-9 2,5-bis-aziridin-1-yl-3,6-dibromo-[1,4]benzoquinone