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439108-60-8

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439108-60-8 Usage

Description

(5-PHENYL-2-THIENYL)METHANOL, with the molecular formula C12H10OS, is a white solid chemical compound at room temperature. It features a phenyl group and a thienyl group, making it a versatile building block for the synthesis of complex organic molecules. (5-PHENYL-2-THIENYL)METHANOL is also recognized for its potential biological activity, as it has been studied for its antifungal and antiviral properties. Furthermore, it serves as a reagent in organic synthesis reactions, allowing the introduction of the (5-phenyl-2-thienyl)methanol functional group into various compounds. (5-PHENYL-2-THIENYL)METHANOL is a valuable chemical with a broad spectrum of applications in the fields of chemistry and pharmaceuticals.

Uses

Used in Chemical Synthesis:
(5-PHENYL-2-THIENYL)METHANOL is used as a versatile building block for the synthesis of complex organic molecules due to its phenyl and thienyl groups.
Used in Pharmaceutical Applications:
(5-PHENYL-2-THIENYL)METHANOL is used as a compound with potential biological activity, particularly for its antifungal and antiviral properties.
Used in Organic Synthesis Reactions:
(5-PHENYL-2-THIENYL)METHANOL is used as a reagent to introduce the (5-phenyl-2-thienyl)methanol functional group into various compounds, enhancing their properties and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 439108-60-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,9,1,0 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 439108-60:
(8*4)+(7*3)+(6*9)+(5*1)+(4*0)+(3*8)+(2*6)+(1*0)=148
148 % 10 = 8
So 439108-60-8 is a valid CAS Registry Number.

439108-60-8Relevant articles and documents

Metal-Free Aerobic Oxidative Selective C-C Bond Cleavage in Heteroaryl-Containing Primary and Secondary Alcohols

Xia, Anjie,Qi, Xueyu,Mao, Xin,Wu, Xiaoai,Yang, Xin,Zhang, Rong,Xiang, Zhiyu,Lian, Zhong,Chen, Yingchun,Yang, Shengyong

, (2019/05/07)

A transition-metal-free aerobic oxidative selective C-C bond-cleavage reaction in primary and secondary heteroaryl alcohols is reported. This reaction was highly efficient and tolerated various heteroaryl alcohols, generating a carboxylic acid derivative and a neutral heteroaromatic compound. Experimental studies combined with density functional theory calculations revealed the mechanism underlying the selective C-C bond cleavage. This strategy also provides an alternative simple approach to carboxylation reaction.

Oxazolidinone compound containing piperazine hydrazone structure

-

Paragraph 0157; 0158, (2017/09/02)

The invention discloses an oxazolidinone compound containing a piperazine hydrazone structure. The oxazolidinone compound comprises a compound shown as a general formula (I), or stereisomer thereof, or pharmaceutically-acceptable salt thereof, or solvate thereof or prodrug thereof, wherein R1 is hydrogen, fluorine, chlorine or trifluoromethyl, R2 is -NHCOCH3 or -OH, R3 is Ar which is C5-C10 aryl substituted by any 1-3 R4 and heteroaryl, and R4 is hydrogen, hydroxyl, halogen, nitro, amino, cyan, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkyl substituted by hydroxyl, amino or halogen, C1-C6 alkoxy substituted by hydroxyl, amino or halogen, amino substituted by mono- or bi-(C1-C6 alkyl), C1-C6 alkyl amido, free, salty, esterified and amidated hydroxyl, C1-C6 alkyl sulfinyl, C1-C6 alkyl sulfonyl, C1-C6 alkyl acyl and carbamoyl. The oxazolidinone compound can be used for preparing drug for treating microbial infection.

First selective CYP11B1 inhibitors for the treatment of cortisol-dependent diseases

Hille, Ulrike E.,Zimmer, Christina,Vock, Carsten A.,Hartmann, Rolf W.

, p. 2 - 6 (2011/04/17)

Outgoing from an etomidate-based design concept, we succeeded in the development of a series of highly active and selective inhibitors of CYP11B1, the key enzyme of cortisol biosynthesis, as potential drugs for the treatment of Cushing's syndrome and rela

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