4416-67-5

Basic information

• Product Name: 2-methoxyphenyl 4-methylbenzenesulfonate
• Synonyms: 2-methoxyphenyl 4-methylbenzenesulfonate
• CAS NO: 4416-67-5
• Molecular Formula: C₁₄H₁₄O₄S
• Molecular Weight: 278.32356
• Mol File: 4416-67-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 427°Cat760mmHg
• Flash Point: 212°C
• Appearance: /
• Density: 1.245g/cm³
• Vapor Pressure: 4.23E-07mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: 2-methoxyphenyl 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxyphenyl 4-methylbenzenesulfonate(4416-67-5)
• EPA Substance Registry System: 2-methoxyphenyl 4-methylbenzenesulfonate(4416-67-5)

Safety Data

• Hazardous Substances Data: 4416-67-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H14O4S/c1-11-7-9-12(10-8-11)19(15,16)18-14-6-4-3-5-13(14)17-2/h3-10H,1-2H3

Upstream product

• 90-05-1 2-methoxy-phenol 
• 98-59-9 p-toluenesulfonyl chloride 
• 91-16-7 1,2-dimethoxybenzene 
• 137669-12-6 Toluene-4-sulfonic acid 2-methoxy-6-(1-phenyl-1H-tetrazol-5-yloxy)-phenyl ester 
• 135-19-3 β-naphthol 
• 773872-07-4 4-(hydroxymethyl)-2-methoxyphenyl 4-methylbenzenesulfonate 
• 498-00-0 4-hydroxymethyl-2-methoxyphenol 
• 1017246-78-4 10-(2-methoxyphenyl)phenothiabismine 5,5-dioxide 
• 104-15-4 toluene-4-sulfonic acid 
• 137669-00-2 2,3-bis(tosyloxy)anisole 
• 137669-08-0 3-hydroxy-2-(tosyloxy)anisole 
• 934-00-9 3-methocycatechol 
• 28165-49-3 6-bromoguaiacol 

Downstream Products

• 86-26-0 2-methoxy-1,1'-biphenyl 
• 910629-23-1 5-iodo-2-methoxyphenyl 4-methylbenzenesulfonate 
• 1048028-27-8 3-(2-methoxybenzyl)benzoic acid ethyl ester 
• 1253579-70-2 1,2-dimethoxy-4-(2-methoxy-phenylethynyl)-benzene 
• 6609-56-9 2-methoxy-benzonitrile 
• 27347-13-3 N-(2-methoxyphenyl)morpholine 
• 100-66-3 methoxybenzene 
• 59099-58-0 2-methoxyphenyl triflate 
• 90-05-1 2-methoxy-phenol 
• 4877-93-4 2,2'-Dimethoxybiphenyl 
• 2364-62-7 n-butyl o-methoxybenzoate 
• 88105-14-0 (2-methoxyphenyl)-tert-butylamino-methanone 
• 89625-43-4 (S)-4-Acetoxy-2-({benzoyl-[2-bromo-4-methoxy-5-(toluene-4-sulfonyloxy)-phenyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 89625-40-1 (S)-4-Acetoxy-2-[2-bromo-4-methoxy-5-(toluene-4-sulfonyloxy)-phenylcarbamoyl]-pyrrolidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Direct C-H Cyanation of Arenes via Organic Photoredox Catalysis

Methods for the direct C-H functionalization of aromatic compounds are in demand for a variety of applications, including the synthesis of agrochemicals, pharmaceuticals, and materials. Herein, we disclose the construction of aromatic nitriles via direct C-H functionalization using an acridinium photoredox catalyst and trimethylsilyl cyanide under an aerobic atmosphere. The reaction proceeds at room temperature under mild conditions and has proven to be compatible with a variety of electron-donating and -withdrawing groups, halogens, and nitrogen- and oxygen-containing heterocycles, as well as aromatic-containing pharmaceutical agents.

Chromatography-Free and Eco-Friendly Synthesis of Aryl Tosylates and Mesylates

Two chromatography-free and eco-friendly protocols have been developed to synthesize aryl tosylates and mesylates by the tosylation and mesylation of the corresponding hydroxyarenes, respectively. These protocols are superior to other known ones regarding

Aminocarbonylation of Aryl Tosylates to Carboxamides

The palladium - catalyzed aminocarbonylation of aryl tosylates with amines is reported. Suitable conditions were identified by high throughput reaction screening and then further optimized. The substrate scope of the reaction with respect to the aryl tosylate component and the amine component are reported. Competitive aminolysis of the aryl tosylates to afford the amine toluenesulfonamides and the phenol was not observed.