446-20-8

Basic information

• Product Name: 4-AMino-2-fluoro-5-nitroanisole[5-Fluoro-4-Methoxy-2-nitroaniline]
• Synonyms: 4-AMino-2-fluoro-5-nitroanisole[5-Fluoro-4-Methoxy-2-nitroaniline];4-Amino-2-fluoro-5-nitroanisole;5-Fluoro-4-methoxy-2-nitroaniline;NSC 1133;5-Fluoro-4-methoxy-2-nitro-phenylamine
• CAS NO: 446-20-8
• Molecular Formula: C₇H₇FN₂O₃
• Molecular Weight: 186.1404832
• Mol File: 446-20-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 142.5-143.5 °C
• Boiling Point: 355.4°C at 760 mmHg
• Flash Point: 168.7°C
• Appearance: /
• Density: 1.412g/cm³
• Vapor Pressure: 3.14E-05mmHg at 25°C
• Refractive Index: 1.577
• PKA: -0.18±0.25(Predicted)
• CAS DataBase Reference: 4-AMino-2-fluoro-5-nitroanisole[5-Fluoro-4-Methoxy-2-nitroaniline](CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMino-2-fluoro-5-nitroanisole[5-Fluoro-4-Methoxy-2-nitroaniline](446-20-8)
• EPA Substance Registry System: 4-AMino-2-fluoro-5-nitroanisole[5-Fluoro-4-Methoxy-2-nitroaniline](446-20-8)

Safety Data

• Hazardous Substances Data: 446-20-8(Hazardous Substances Data)

Usage

General Description

4-Amino-2-fluoro-5-nitroanisole is a chemical compound with a molecular formula C7H6FNO3. It is an aromatic amine and a nitro compound, with a molecular weight of 173.13 g/mol. 4-AMino-2-fluoro-5-nitroanisole[5-Fluoro-4-Methoxy-2-nitroaniline] has potential applications in pharmaceutical and chemical synthesis. On the other hand, 5-Fluoro-4-Methoxy-2-nitroaniline is a chemical compound with a molecular formula C7H7FN2O3. It is an aromatic amine and a nitro compound, with a molecular weight of 182.14 g/mol. 4-AMino-2-fluoro-5-nitroanisole[5-Fluoro-4-Methoxy-2-nitroaniline] has potential applications in pharmaceutical and chemical synthesis. Both of these chemicals have potential applications in organic synthesis and as intermediates in the production of pharmaceuticals and other fine chemicals.

InChI:InChI=1/C7H7FN2O3/c1-13-7-3-6(10(11)12)5(9)2-4(7)8/h2-3H,9H2,1H3

Upstream product

• 366-99-4 3-fluoro-4-methoxyaniline 
• 452-15-3 N-(3-fluoro-4-methoxyphenyl)acetamide 
• 321-28-8 1-fluoro-2-methoxybenzene 
• 448-26-0 N-(5-fluoro-4-methoxy-2-nitrophenyl)acetamide 
• 455-93-6 2-fluoro-1-methoxy-4-nitrobenzene 

Downstream Products

• 125163-15-7 4-Fluoro-5-methoxy-1,2-phenylenediamine 
• 661463-13-4 4-bromo-2-fluoro-5-nitrophenyl methyl ether 
• 76185-43-8 4-methyl-5-fluoro-6-methoxy-8-<(4-amino-1-methylbutyl)amino>quinoline maleate 
• 76100-57-7 4,5-dimethyl-6-methoxy-8-<(4-amino-1-methylbutyl)amino>quinoline maleate 
• 170809-21-9 5-fluoro-6-methoxy-8-aminoquinoline 

Relevant articles and documents

Benzimidazole compound, and preparation method, intermediate and application thereof

The invention discloses a benzimidazole compound, and a preparation method, an intermediate and an application thereof. The invention provides a benzimidazole compound A or a pharmaceutically-acceptable salt thereof, and also provides an application of th

COUMARIN DERIVATIVE AND USE THEREOF

The present invention relates to an alkaline earth metal salt or an organic amine salt of a compound represented by the formula [I]: wherein R1 and R2 are each a hydrogen atom, a halogen atom, or an optionally substituted linear hydrocarbon group; ring A is an optionally further substituted benzene ring; B is an optionally substituted benzene ring; R is a carboxyl group or a linear hydrocarbon group substituted with a carboxyl group and the like.

4-Methyl-5-(unsubstituted and substituted phenoxy)-6-methoxy-8-(aminoalkylamino)quinolines

Compounds of the class including 4-methyl-5-(unsubstituted and substitutedhenoxy)-6-methoxy-8-(aminoalkylamino)quinolines as the free bases and pharmaceutically acceptable acid amine salts are described. The compounds are highly effective antimalarial agents which possess, surprisingly, both tissue schizonticidal (radical curative) and blood schizonticidal (suppressive) activity. In addition, these drugs have significantly better therapeutics indices than primaquine which is the current tissue schizonticidal drug of choice. Primaquine possesses no useful blood schizonticidal activity at tolerated dose levels.