446-62-8

Basic information

• Product Name: 6,7-Dichloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
• Synonyms: 6,7-Dichloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
• CAS NO: 446-62-8
• Molecular Formula: C8H8Cl2N2O2S
• Molecular Weight: 0
• Mol File: 446-62-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 421.6°C at 760 mmHg
• Flash Point: 208.8°C
• Appearance: /
• Density: 1.494g/cm³
• Vapor Pressure: 2.58E-07mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 6,7-Dichloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-Dichloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide(446-62-8)
• EPA Substance Registry System: 6,7-Dichloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide(446-62-8)

Safety Data

• Hazardous Substances Data: 446-62-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H8Cl2N2O2S/c1-4-11-7-2-5(9)6(10)3-8(7)15(13,14)12-4/h2-4,11-12H,1H3

Upstream product

• 75-07-0 acetaldehyde 
• 16948-63-3 2-amino-4,5-dichlorobenzenesulfonamide 

Relevant articles and documents

Energy barrier determination of enantiomerization of chiral 3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide type compounds by enantioselective stopped-flow HPLC

The synthesis and enantioseparation of chiral 3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide derivatives are reported herein. A HPLC stopped-flow procedure was applied to the determination of rate constants and free energy barriers of enantiomerization of the compounds synthesized in the presence of achiral stationary phase. The individual enantiomers of the studied compounds were isolated in parallel by preparative HPLC on a Chiraspher NT column. Rate constants and free energy barriers of enantiomerization were determined in the mobile phase. The results were used to determine the influence of the chiral stationary phase on the enantiomerization process.