447-93-8 Usage
Description
3-Methoxy-4-(trifluoromethyl)benzonitrile, 97% is a chemical compound characterized by its molecular structure that features a methoxy group, a trifluoromethyl group, and a nitrile group attached to a benzene ring. 3-Methoxy-4-(trifluoroMethyl)benzonitrile, 97% is typically available in a purity of 97%, making it a valuable intermediate for various chemical syntheses.
Uses
Used in Pharmaceutical Industry:
3-Methoxy-4-(trifluoromethyl)benzonitrile, 97% is used as a reagent for the synthesis of pyridine and pyrimidine derivatives, which are known as mGluR2 antagonists. These antagonists play a crucial role in the development of medications targeting neurological disorders and conditions related to glutamate signaling.
Used in Chemical Synthesis:
3-Methoxy-4-(trifluoromethyl)benzonitrile, 97% serves as an essential intermediate in the synthesis of various organic compounds, particularly those with potential applications in the pharmaceutical, agrochemical, and materials science industries. Its unique functional groups allow for further chemical reactions and modifications, making it a versatile building block in the development of new molecules with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 447-93-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,4 and 7 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 447-93:
(5*4)+(4*4)+(3*7)+(2*9)+(1*3)=78
78 % 10 = 8
So 447-93-8 is a valid CAS Registry Number.
447-93-8Relevant articles and documents
PYRIDINE AND PYRIMIDINE DERIVATIVES AS MGIUR2 ANTAGONISTS
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Page/Page column 39, (2010/11/29)
The present invention relates to compounds of formula (I), a process for the manufacture thereof, pharmaceutical compositions containing them, and their use for treating CNS disorders:wherein A, B, X, Y, R1, R2, R3 and R4 are as defined in the description and claims.
Process for producing trifluoromethylbenzylamines
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, (2008/06/13)
The invention relates to a process for producing a trifluoromethylbenzylamine represented by the following general formula (1). This process includes hydrogenating a trifliuoromethylbenzonitrile represented by the following general formula (2) by hydrogen in an organic solvent in the presence of ammonia, using a Raney catalyst, where each R independently represents a halogen selected from the group consisting of fluorine, chlorine, bromine and iodine, an alkyl group having a carbon atom number of 1-4, an alkoxy group having a carbon atom number of 1-4, an amino group, a hydroxyl group or a trifluoromethyl group, and n represents an integer from 0 to 4, where R and n are defined as above. With this process, it is possible to obtain the trifluoromethylbenzylamine easily and inexpensively at an extremely high yield.
