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448959-69-1

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448959-69-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 448959-69-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,8,9,5 and 9 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 448959-69:
(8*4)+(7*4)+(6*8)+(5*9)+(4*5)+(3*9)+(2*6)+(1*9)=221
221 % 10 = 1
So 448959-69-1 is a valid CAS Registry Number.

448959-69-1Relevant articles and documents

NOVEL LYSOPHOSPHATIDIC ACID RECEPTOR SELECTIVE ANTAGONISTS

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Page/Page column 79, (2008/06/13)

The present invention is directed to compositions comprising lysophosphatidic acid analogs and methods of using such analogs as agonist or antagonists of LPA receptor activity. In addition the invention is directed to LPA receptor agonists that vary in the degree of selectivity at individual LPA receptors (i.e. LPA1, LPA2 and LPA3). More particularly the present invention is directed to LPA analogs wherein the glycerol is replaced with ethanolamine and a variety of substitutions have been linked at the second carbon atom.

Synthesis of Para-alkyl aryl amide analogues of sphingosine-1-phosphate: Discovery of potent S1P receptor agonists

Clemens, Jeremy J.,Davis, Michael D.,Lynch, Kevin R.,Macdonald, Timothy L.

, p. 3401 - 3404 (2007/10/03)

Sphingosine-1-phosphate (S1P) is a biologically active lysophospholipid with the capacity to induce a broad range of cellular responses via its interaction with the S1P family of G-protein coupled receptors. This report describes the synthesis of several

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