450-89-5

Basic information

• Product Name: 2-CHLORO-5-FLUOROANISOLE
• Synonyms: 1-CHLORO-4-FLUORO-2-METHOXYBENZENE;2-CHLORO-5-FLUOROANISOLE;2-Chloro-5-fluoroanisole 98%;2-Chloro-5-fluoroanisole98%;1-Chloro-2-methoxy-4-fluorobenzene;2-Chloro-5-fluoroanisole,97%;2-Chloro-5-fluoroanisole1-Chloro-4-fluoro-2-methoxybenzene;2-Chloro-5-flouroanisole
• CAS NO: 450-89-5
• Molecular Formula: C₇H₆ClFO
• Molecular Weight: 160.57
• Product Categories: Anisole;Anisoles, Alkyloxy Compounds & Phenylacetates;Chlorine Compounds;Fluorine Compounds
• Mol File: 450-89-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 195 °C / 757mmHg
• Flash Point: 57.2 °C
• Appearance: Clear colorless/Liquid
• Density: 1.28
• Vapor Pressure: 1.9mmHg at 25°C
• Refractive Index: 1.519
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-CHLORO-5-FLUOROANISOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-5-FLUOROANISOLE(450-89-5)
• EPA Substance Registry System: 2-CHLORO-5-FLUOROANISOLE(450-89-5)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38-36/38
• Safety Statements: 16-26-36-37/39-35-28-15-3/9
• RIDADR: 1993
• Hazardous Substances Data: 450-89-5(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR COLOURLESS LIQUID

InChI:InChI=1/C7H6ClFO/c1-10-7-4-5(9)2-3-6(7)8/h2-4H,1H3

Upstream product

• 450-91-9 4-fluoro-2-methoxyaniline 
• 448-19-1 4-fluoro-2-methoxy-1-nitrobenzene 
• 3827-49-4 2-chloro-5-fluoro-phenol 
• 74-88-4 methyl iodide 
• 1435-44-5 1-chloro-2,4-difluorobenzene 
• 865-33-8 potassium methanolate 

Downstream Products

• 698983-69-6 2-chloro-1-(5-chloro-2-fluoro-4-hydroxyphenyl)ethanone 
• 450-93-1 2-methoxy-4-fluorophenol 
• 1208076-24-7 1-chloro-4-fluoro-2-methoxy-3-methylbenzene 
• 1357103-75-3 N-benzyl-3-fluoro-5-methoxy-4-methylaniline 
• 1357103-76-4 3-fluoro-5-methoxy-4-methylaniline 
• 932374-66-8 2-chloro-4-nitro-5-fluoroanisole 
• 102392-11-0 1-(4-fluoro-2-methoxyphenyl)piperazine 

Relevant articles and documents

N-(SUBSTITUTED-PHENYL)-SULFONAMIDE DERIVATIVES AS KINASE INHIBITORS

The invention relates to N-(substituted-phenyl)-sulfonamide compounds, which are extremely useful as inhibitors of protein kinases (e.g. PERK kinase) and accordingly can be used for the treatment of cell proliferative disorders, such as cancer, or diseases associated with activated unfolded protein response pathways, such as Alzheimer's disease. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.