452-07-3 Usage
General Description
2,4-Difluorobenzyl chloride is an organic compound with the chemical formula C7H5ClF2. It is a colorless liquid with a strong and pungent odor. This chemical is commonly used as an intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a reagent in organic synthesis, particularly in the preparation of various fluorinated compounds. 2,4-Difluorobenzyl chloride is a versatile building block in chemical reactions and is known for its ability to introduce fluorine atoms into organic molecules, making it a valuable compound in the pharmaceutical and agrochemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 452-07-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,5 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 452-07:
(5*4)+(4*5)+(3*2)+(2*0)+(1*7)=53
53 % 10 = 3
So 452-07-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClF2/c8-4-5-1-2-6(9)3-7(5)10/h1-3H,4H2
452-07-3Relevant articles and documents
2. 4 - difluorobenzene methylamine synthetic method
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Paragraph 0036-0040, (2017/10/22)
The invention relates to the fields of medicine and agrochemicals, and concretely relates to a synthetic method of an intermediate 2,4-difluorobenzene methylamine. The synthetic method comprises the following steps: 1) m-difluorobenzene, a halogenating agent and paraformaldehyde are reacted under effect of a catalyst to prepare 2,4-difluoro benzyl halide; 2)the prepared 2,4-difluoro benzyl halide and urotropine are reacted to prepare a quaternary ammonium salt compound IV; 3)the prepared quaternary ammonium salt compound is hydrolyzed by concentrated hydrochloric acid to obtain 2,4-difluorobenzene methylamine. The method has the advantages of low cost of the prepared 2,4-difluorobenzene methylamine, convenient operation and high security coefficient, and is suitable for industrial production.