453-33-8

Basic information

• Product Name: 3-Penten-2-one, 5,5,5-trifluoro-4-hydroxy-
• Synonyms: 3-Penten-2-one, 5,5,5-trifluoro-4-hydroxy-
• CAS NO: 453-33-8
• Molecular Formula: C₅H₅F₃O₂
• Molecular Weight: 0
• Mol File: 453-33-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Penten-2-one, 5,5,5-trifluoro-4-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Penten-2-one, 5,5,5-trifluoro-4-hydroxy-(453-33-8)
• EPA Substance Registry System: 3-Penten-2-one, 5,5,5-trifluoro-4-hydroxy-(453-33-8)

Safety Data

• Hazardous Substances Data: 453-33-8(Hazardous Substances Data)

Upstream product

• 383-63-1 ethyl trifluoroacetate, 
• 67-64-1 acetone 

Downstream Products

• 583-05-1 1-phenylpentane-1,4-dione 

Relevant articles and documents

Highly enantioselective construction of 3-hydroxy oxindoles through a decarboxylative aldol addition of trifluoromethyl α-fluorinated gem-diols to n-benzyl isatins

An organocatalytic asymmetric direct aldol addition reaction that involves cleavage of a carbon-carbon bond through the release of trifluoroacetate was developed. The protocol is wide in scope, generating the desired oxindoles of biological interest in nearly quantitative yields (up to 99 %) with excellent enantioselectivities (up to 98 % ee) and diastereoselectivities (up to 99:1 d.r.). Copyright