4532-33-6

Basic information

• Product Name: 1-Methoxy-3-Methylcarbazole
• Synonyms: 1-Methoxy-3-Methylcarbazole;1-Methoxy-3-Methyl-9H-carbazole;Murrayafoline A
• CAS NO: 4532-33-6
• Molecular Formula: C₁₄H₁₃NO
• Molecular Weight: 211.25912
• Mol File: 4532-33-6.mol
• Article Data: 30

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-Methoxy-3-Methylcarbazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methoxy-3-Methylcarbazole(4532-33-6)
• EPA Substance Registry System: 1-Methoxy-3-Methylcarbazole(4532-33-6)

Safety Data

• Hazardous Substances Data: 4532-33-6(Hazardous Substances Data)

Usage

General Description

1-Methoxy-3-Methylcarbazole is a chemical compound with the molecular formula C14H13NO. It is an aromatic compound that is commonly used in the production of OLEDs (organic light-emitting diodes) as a hole-transport material. 1-Methoxy-3-Methylcarbazole is known for its high thermal stability and good film-forming properties, making it suitable for use in electronic devices. It also exhibits fluorescent properties, which makes it useful in various applications such as organic semiconductors, photovoltaic devices, and sensors. Additionally, 1-Methoxy-3-Methylcarbazole has been studied for its potential use as an anticancer agent due to its cytotoxic effects on cancer cells. Overall, this chemical compound has diverse applications in the fields of electronics, materials science, and biomedicine.

Upstream product

• 14960-81-7 1-hydroxy-3-methyl-9H-carbazole 
• 77-78-1 dimethyl sulfate 
• 103763-41-3 4-hydroxy-1-indol-2-yl-3-methylbutan-1-one 
• 103763-38-8 4,5-dihydro-3-indol-2-ylcarbonyl-4-methylfuran-2-one 
• 74204-00-5 3-bromo-5-methylphenol 
• 796061-07-9 4-methyl-N-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzenesulfonamide 
• 29578-83-4 3-bromo-5-methoxytoluene 
• 100-63-0 phenylhydrazine 
• 14961-29-6 3-methyl-1,2,3,4-tetrahydro-9H-carbazole-1-one 
• 6933-54-6 3-methyl-2,3,4,9-tetrahydro-1H-carbazole 
• 62-53-3 aniline 
• 1421367-18-1 6-diazo-3-methyl-2-cyclohexen-1-one 
• 1451422-45-9 2-(2-methoxy-4-methylphenyl)hydrazonocyclohexanone 
• 108-39-4 3-methyl-phenol 

Downstream Products

• 89368-89-8 1-methoxy-9-[(1-methoxycarbazol-3-yl)-methyl]-3-methylcarbazole 
• 1397693-64-9 C₃₆H₃₀N₂O₆S 
• 1430117-65-9 9-((4((tert-butyldiphenylsilyloxy)methyl)-1H-1,2,3-triazol-1-yl)propyl)-1-methoxy-3-methyl-9H-carbazole 
• 1430117-69-3 9-(3-(4-((4-(2,5-difluorobenzyl)piperazin-1-yl)methyl)-1H-1,2,3-triazol-1-yl)propyl)-1-methoxy-3-methyl-9H-carbazole 
• 1430117-68-2 1-methoxy-3-methyl-9-(3-(4-(3-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-1-yl)propyl)-9H-carbazole 
• 1430117-67-1 9-(3-(4-(3,5-difluorophenyl)-1H-1,2,3-triazol-1-yl)propyl)-1-methoxy-3-methyl-9H-carbazole 
• 723-97-7 murrayanine 
• 100108-66-5 murrayaquinone A 
• 14960-81-7 1-hydroxy-3-methyl-9H-carbazole 

Relevant articles and documents

DIMERIC MURRAYAFOLINE A, A POTENTIAL BIS-CARBAZOLE ALKALOID: 'BIOMIMETIC' SYNTHESIS, ATROPOISOMER SEPARATION, AND ANTIMALARIAL ACTIVITY

The first total synthesis of a (potential) dimeric carbazole alkaloid is described.After an improved preparation of the monomeric building block, 'biomimetic dimerization' by oxidative phenolic coupling was best achieved with di-tert-butyl peroxide in chlorobenzene, leading to a highly selective formation of the 2,2'-coupled 'dimer', the parent framework of several naturally occurring dimeric carbazole alkaloids.For the atropoenantiomer analysis, a chromatographic procedure on chiral phase was developed.Both the mono- and the dimeric phenolic carbazoles displayed in vitro antimalarial activity against Plasmodium falciparum.

New syntheses of murrayafoline-A and murrayaquinone-A via Fischer indolization of 2-sulfonyloxyphenylhydrazone (Fischer indolization and its related compounds. Part 29)

Two carbazole alkaloids, murrayafoline-A (4a) and murrayaquinone-A (4b), were synthesized from 1, 2, 3, 4-tetrahydro-8-methanesulfonyloxy-6- methylcarbazole (8) prepared in the application of Fischer indolization of 2- sulfonyloxyphenylhydrazone.

Total synthesis of carbazole alkaloids

A Suzuki-Miyaura cross coupling, followed by triphenylphosphine mediated Cadogan reductive cyclization sequence provided efficient access to a series of carbazole alkaloids. In the present work, this approach was applied to the total synthesis of mukonine, clauszoline K, koenoline, murrayanine, murrayafoline A, mukoeic acid, glycoborine, glycozolicine, mukolidine, mukoline, glycozoline, 3-methoxy-9H-carbazole-1-carboxylic acid methyl ester, (3-methoxy-9H-carbazol-1-yl)-methanol, 3-methoxy-9H-carbazole-1-carbaldehyde, 3-methoxy-9H-carbazole-1-carboxylic acid, 2-methyl-9H-carbazole and nonsteroidal anti-inflammatory drug (NSAID) carprofen and its derivatives.

Synthesis of Methylene-Bridged Biscarbazole Alkaloids by using an Ullmann-type Coupling: First Total Synthesis of Murrastifoline-C and Murrafoline-E

We describe the total synthesis of methylene-bridged biscarbazole alkaloids by using a late-stage Ullmann-type coupling of fully functionalised carbazole subunits. The carbazole derivatives were synthesised via a sequence of palladium(0)- and palladium(II