455-36-7 Usage
Description
3'-Fluoroacetophenone is a clear, colorless to yellow liquid that is utilized as a raw material and intermediate in various industries, including organic synthesis, pharmaceuticals, agrochemicals, and dyes. It is derived through the bio-reduction process using cells of Aspergillus terreus in a phosphate buffer solution-glycerol.
Uses
Used in Organic Synthesis:
3'-Fluoroacetophenone is used as a raw material and intermediate for the synthesis of various organic compounds. Its unique chemical structure allows it to be a versatile building block in the creation of complex molecules.
Used in Pharmaceuticals:
In the pharmaceutical industry, 3'-Fluoroacetophenone is employed as a key intermediate in the development of new drugs. Its properties make it suitable for the synthesis of various medicinal compounds, contributing to the advancement of pharmaceutical research and drug discovery.
Used in Agrochemicals:
3'-Fluoroacetophenone is used as a starting material in the production of agrochemicals, such as pesticides and herbicides. Its role in this industry is crucial for the development of effective and environmentally friendly solutions for agricultural needs.
Used in Dyestuffs:
In the dyestuffs industry, 3'-Fluoroacetophenone is utilized as a raw material for the synthesis of various dyes and pigments. Its chemical properties make it an essential component in the creation of a wide range of colorants used in different applications, such as textiles, plastics, and inks.
Check Digit Verification of cas no
The CAS Registry Mumber 455-36-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,5 and 5 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 455-36:
(5*4)+(4*5)+(3*5)+(2*3)+(1*6)=67
67 % 10 = 7
So 455-36-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H7FO/c1-6(10)7-3-2-4-8(9)5-7/h2-5H,1H3
455-36-7Relevant articles and documents
Visible light-mediated, high-efficiency oxidation of benzyl to acetophenone catalyzed by fluorescein
Geng, Haoxing,Liu, Xin,Zhu, Qing
supporting information, (2021/12/20)
An environmentally friendly aerobic oxidation of benzyl C(sp3)-H bonds to ketones via selective oxidation catalysis was developed. Fluorescein is an efficient photocatalyst with excellent chemical selectivity. The reaction has a wide substrate scope, and a successful gram-scale experiment demonstrated its potential industrial utility.
Photoinduced Acetylation of Anilines under Aqueous and Catalyst-Free Conditions
Yang, Yu-Ming,Yan, Wei,Hu, Han-Wei,Luo, Yimin,Tang, Zhen-Yu,Luo, Zhuangzhu
, p. 12344 - 12353 (2021/09/02)
A green and efficient visible-light induced functionalization of anilines under mild conditions has been reported. Utilizing nontoxic, cost-effective, and water-soluble diacetyl as photosensitizer and acetylating reagent, and water as the solvent, a variety of anilines were converted into the corresponding aryl ketones, iodides, and bromides. With advantages of environmentally friendly conditions, simple operation, broad substrate scope, and functional group tolerance, this reaction represents a valuable method in organic synthesis.
Redox-driven deracemization of secondary alcohols by sequential ether/O2-mediated oxidation and Ru-catalyzed asymmetric reduction
Yang, Bing,Cui, Peng,Chen, Yongsheng,Liu, Qixing,Zhou, Haifeng
supporting information, (2020/10/14)
The deracemization of benzylic alcohols has been achieved using a redox-driven one-pot two-step process. The racemic alcohols were oxidized by bis(methoxypropyl) ether and oxygen to give the ketone intermediates, followed by an asymmetric transfer hydrogenation with a chiral ruthenium catalyst. This compatible oxidation/reduction process gave the enantiomerically enriched alcohols with up to 95% ee values.
