4575-74-0

Basic information

• Product Name: (9β)-9,19-Cyclolanostan-3β-ol acetate
• Synonyms: (9β)-3β-Acetoxy-9,19-cyclo-5α-lanostane;(9β)-9,19-Cyclolanostan-3β-ol acetate;9,19-Cyclolanostan-3β-ol acetate;Cycloartanyl Acetate
• CAS NO: 4575-74-0
• Molecular Formula: C32H54O2
• Molecular Weight: 470.76996
• Mol File: 4575-74-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 132-133 °C
• Boiling Point: 460.7±13.0 °C(Predicted)
• Appearance: /
• Density: 1.00±0.1 g/cm3(Predicted)
• CAS DataBase Reference: (9β)-9,19-Cyclolanostan-3β-ol acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (9β)-9,19-Cyclolanostan-3β-ol acetate(4575-74-0)
• EPA Substance Registry System: (9β)-9,19-Cyclolanostan-3β-ol acetate(4575-74-0)

Safety Data

• Hazardous Substances Data: 4575-74-0(Hazardous Substances Data)

Upstream product

• 1259-10-5 cycloartenyl acetate 
• 4657-58-3 cycloartanol 
• 108-24-7 acetic anhydride 
• 1259-10-5 cycloartenol acetate 
• 1259-10-5 cycloroylenyl acetate 
• 1259-10-5 Acetic acid (3S,9S,13R,14S,17R)-17-((R)-1,5-dimethyl-hex-4-enyl)-4,4,13,14-tetramethyl-tetradecahydro-cyclopropa[9,10]cyclopenta[a]phenanthren-3-yl ester 
• 1259-94-5 24⁽²⁸⁾-methylenecycloartenyl acetate 
• 511-63-7 cycloart-24-en-3-one 
• 469-38-5 handianol 
• 4936-10-1 9,19-cyclolanostan-3-one 
• 70587-99-4 Isocycloartenolacetat 
• 1259-95-6 24-oxo-cycloartan-3β-yl acetate 

Downstream Products

• 1180-88-7 24-Dihydroparkeol-acetat 
• 1180-88-7 δ^9,11-dihydroroylenyl acetate 
• 6562-14-7 3β-Acethoxy-5α-lanostan 
• 55724-72-6 3β-acetoxy-lanost-9(11)-en-12-one 
• 28032-52-2 5α-Lanost-9(11)-en-3β-ol 
• 1724-19-2 δ^8,9-dihydroeupholacetate 
• 4657-58-3 cycloartanol 
• 99946-06-2 cycloart-25-en-3b,24-diol 
• 54482-57-4 (23E)-25-hydroxycycloart-23-ene-3β,25-diol 
• 1180-88-7 3β-acetoxy-5α-lanost-9(11)-ene 

Relevant articles and documents

Cycloarta-16,24-dien-3β-ol: Revised structure of cimicifugenol, a cycloartane triterpenoid

The structure of a triterpene alcohol isolated from the nonsaponifiable lipids of both the root and aerial part extracts of Cimicifuga simplex (Ranunculaceae) was established to be cycloarta-16,24-dien-3β-ol (1). Spectral identity of the 24,25-dihydro derivative (4) of 1 with 24,25- dihydrocimicifugenol demonstrated that cimicifugenol, previously assigned the erroneous structure of cycloarta-7,24-dien-3β-ol, possesses structure 1.

Cytotoxic triterpenoids from the leaves of Euphorbia pulcherrima

Two cytotoxic triterpenes have been isolated from Euphorbia pulcherrima. Their structures and stereochemistry have been established from NMR, IR, and EI-mass spectroscopy. The compounds were identified as 9,19-cycloart-23-ene-3β,25-diol and 9,19-cycloart-25-ene-3β,24-diol. Cytotoxicity evaluation was performed using Ehrlich ascites tumor cells. While cycloartenol induced no cytotoxic activity against Ehrlich ascites tumor cells, both isolated triterpenes exhibited cell inactivating effects. The IC50 is approximately 7.5 μM, while the IC90 is approximately 13.5 μM for 9,19-cycloart-25-ene-3β,24-diol. The 3β,25-diol compound is 50% less active.

Chemical constituents of the alkaloid-free fraction from opium.

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