457658-05-8

Basic information

• Product Name: (3-iodophenyl)urea
• Synonyms: (3-iodophenyl)urea
• CAS NO: 457658-05-8
• Molecular Formula: C₇H₇IN₂O
• Molecular Weight: 262.04775
• Mol File: 457658-05-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-iodophenyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: (3-iodophenyl)urea(457658-05-8)
• EPA Substance Registry System: (3-iodophenyl)urea(457658-05-8)

Safety Data

• Hazardous Substances Data: 457658-05-8(Hazardous Substances Data)

Usage

Description

(3-iodophenyl)urea is a chemical compound that belongs to the class of ureas, which are organic compounds containing the carbonyl group attached to two organic groups with the general formula R1R2NCONH2. In the case of (3-iodophenyl)urea, the R1 and R2 groups are replaced by a 3-iodophenyl group and a urea group, respectively. It has a molecular formula of C7H7IN2O, and its structure consists of a urea group linked to a 3-iodophenyl group. (3-iodophenyl)urea is commonly used in chemical synthesis and as a building block in the preparation of various organic compounds. Its properties and applications are largely determined by its chemical structure and reactivity.

Uses

Used in Chemical Synthesis:
(3-iodophenyl)urea is used as a building block for the synthesis of various organic compounds. Its unique structure and reactivity make it a valuable component in the creation of a wide range of chemical products.
Used in Pharmaceutical Industry:
(3-iodophenyl)urea is used as an intermediate in the development of pharmaceutical compounds. Its specific chemical properties allow it to be incorporated into drug molecules, potentially leading to the discovery of new medications with various therapeutic applications.
Used in Research and Development:
(3-iodophenyl)urea is utilized in research and development settings to study the properties and reactions of urea-based compounds. This helps scientists and researchers to better understand the behavior of similar compounds and to develop new methods for their synthesis and application.

Upstream product

• 626-01-7 3-Iodoaniline 
• 917-61-3 sodium isocyanate 
• 590-28-3 potassium cyanate 

Downstream Products

• 603-54-3 N,N-diphenylurea 
• 7664-41-7 ammonia 
• 626-01-7 3-Iodoaniline 
• 594861-88-8 N-(3-{4-[(6-bromohexyl)oxy]but-1-ynyl}phenyl)urea 
• 671777-27-8 1-(3-iodophenyl)-2,4(1H,3H)-pyrimidinedione 

Relevant articles and documents

H-Bonding Assisted Self-Assembly of Anionic and Neutral Ligand on Metal: A Comprehensive Strategy to Mimic Ditopic Ligands in Olefin Polymerization

Self-assembly of two neutral ligands on a metal to mimic bidentate ligand coordination has been frequently encountered in the recent past, but self-assembly of an anionic ligand on a metal template alongside a neutral ligand remains an elusive target. Suc

Highly Enantioselective Pd-Catalyzed Synthesis of P-Stereogenic Supramolecular Phosphines, Self-Assembly, and Implication

Metal-catalyzed asymmetric addition of a secondary phosphine to an aryl halide is one of the most efficient and reliable approaches for the construction of enantiopure carbon-phosphorus bonds. An isolated Pd(II) complex (5) catalyzes the carbon-phosphorus coupling reaction between tolylphenylphosphine (1a) and 3-iodophenylurea (2b), which proceeds with an unprecedented enantiomeric excess (ee) of 97%. The generality of the strategy has been demonstrated by preparing a small library of a new class of P-stereogenic phosphines with an in-built hydrogen bonding motif for the first time. The P-stereogenic phosphines self-assemble on a metal template via deliberately installed hydrogen-bonding motifs and mimic the bidentate ligand coordination. Interestingly, when it was employed in asymmetric hydrogenation, the supramolecular phosphine {1-(3-(phenyl(o-tolyl)phosphanyl)phenyl)urea} (6b) produced the corresponding hydrogenated product with the highest enantiomeric excess of 99% along with excellent conversion, demonstrating the potential of these enantioenriched P-chirogenic supramolecular phosphines in asymmetric catalysis.

PHENETHANOLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF RESPIRATORY DISEASES

The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.