457925-19-8 Usage
Molecular Structure
1H-Pyrazole, 4-phenyl-1-[3-(phenylseleno)propyl]is a chemical compound with a five-membered pyrazole ring, a phenyl group, and a 3-(phenylseleno)propyl group attached to it.
Substitution
The pyrazole ring is substituted by a phenyl group and a 3-(phenylseleno)propyl group.
Reactivity
The phenylseleno group, which contains a selenium atom, can impart unique reactivity and selectivity to the compound, making it useful for late-stage functionalization of complex molecules.
Uses
1H-Pyrazole, 4-phenyl-1-[3-(phenylseleno)propyl]is often used in organic synthesis as a building block for pharmaceuticals and agrochemicals. It may be used in various research and manufacturing applications, particularly in the development of new chemical entities and materials.
Toxicity
Selenium-containing compounds can be toxic if mishandled, so it is important to handle this compound with care.
Check Digit Verification of cas no
The CAS Registry Mumber 457925-19-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,7,9,2 and 5 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 457925-19:
(8*4)+(7*5)+(6*7)+(5*9)+(4*2)+(3*5)+(2*1)+(1*9)=188
188 % 10 = 8
So 457925-19-8 is a valid CAS Registry Number.
457925-19-8Relevant articles and documents
Bu3SnH-mediated radical cyclisation onto azoles
Allin, Steven M.,Barton, William R.S.,Russell Bowman,Bridge (née Mann), Emma,Elsegood, Mark R.J.,McInally, Tom,McKee, Vickie
, p. 7745 - 7758 (2008/12/21)
Alkyl radicals have been cyclised onto pyrroles, imidazoles and pyrazoles, and acyl radicals cyclised onto pyrroles, using Bu3SnH-, (TMS)3SiH- and Bu3GeH-mediated aromatic homolytic substitution for the synthesis of bicyclic N-heterocycles. The reactions yield intermediate π-radicals that lose hydrogen in the?rearomatisation step of the aromatic homolytic substitution. Mechanistic studies of these rearomatisation steps indicate aromatic homolytic substitution in which the initiator or breakdown products from the inhibitor are responsible for the H-abstraction step.
