45815-08-5

Basic information

• Product Name: 2-(Propylamino)pyridine
• Synonyms: 2-(Propylamino)pyridine;N-propyl-2-Pyridinamine
• CAS NO: 45815-08-5
• Molecular Formula: C₈H₁₂N₂
• Molecular Weight: 136.19
• Mol File: 45815-08-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 236 ºC
• Flash Point: 97 ºC
• Appearance: /
• Density: 1.007
• Vapor Pressure: 0.048mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: 2-(Propylamino)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Propylamino)pyridine(45815-08-5)
• EPA Substance Registry System: 2-(Propylamino)pyridine(45815-08-5)

Safety Data

• Hazardous Substances Data: 45815-08-5(Hazardous Substances Data)

Usage

General Description

2-(Propylamino)pyridine is a chemical compound with the formula C8H12N2. It is a pyridine derivative that contains a propylamine group attached to the second position of the pyridine ring. 2-(Propylamino)pyridine is used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceutical products. It can also be used as a reagent in organic synthesis for the preparation of other chemical compounds. 2-(Propylamino)pyridine is a colorless liquid with a strong, unpleasant odor and is classified as a flammable and hazardous substance. It is important to handle and store this chemical with care to prevent accidents or exposure.

InChI:InChI=1/C8H12N2/c1-2-6-9-8-5-3-4-7-10-8/h3-5,7H,2,6H2,1H3,(H,9,10)

Upstream product

• 109-04-6 2-bromo-pyridine 
• 107-10-8 propylamine 
• 504-29-0 2-aminopyridine 
• 802294-64-0 propionic acid 
• 106-94-5 propyl bromide 
• 121953-50-2 N-Propyl-N-pyridin-2-yl-formamide 
• 34813-97-3 2-(formylamino)pyridine 
• 694-59-7 pyridine N-oxide 
• 38427-94-0 N-(tert-butoxycarbonyl)-2-aminopyridine 
• 442513-37-3 propyl-pyridin-2-yl-carbamic acid tert-butyl ester 
• 71-23-8 propan-1-ol 
• 107-08-4 1-iodo-propane 
• 40825-17-0 Natrium-Verbindung des [2]Pyridylamins 
• 599-91-7 propyl tosylate 

Downstream Products

• 893429-17-9 3-{3-[2-(propyl-pyridin-2-yl-amino)-ethoxy]-phenyl}-propionic acid ethyl ester 
• 1176948-87-0 C₁₇H₁₆N₂O₂ 
• 27433-25-6 4-oxo-1-propyl-4H-pyrido[1,2-a]pyrimidinium 

Relevant articles and documents

Dithioacetal-containing pyridopyrimidone derivative as well as preparation and application thereof

The invention relates to a dithioacetal-containing pyridopyrimidone derivative as well as preparation and application thereof. The compound disclosed by the invention has a structure as shown in a formula (I) in the specification, has excellent insecticidal activity on sogatella furcifera, broad bean aphids and the like, and has a relatively good prevention and treatment effect on potato Y viruses at the same time. The compound can be used for preventing and treating hemiptera pests such as rice planthoppers and aphids, and also can be used for preventing and treating plant viruses such as potato Y viruses. The structure and the preparation process are simple, and the production cost is low.

Cationic iridium-catalyzed enantioselective activation of secondary sp 3 C-H bond adjacent to nitrogen atom

A cationic Ir(I)-tolBINAP complex catalyzed an enantioselective C-C bond formation, which was initiated by secondary sp3 C-H bond cleavage adjacent to nitrogen atom. A wide variety of 2-(alkylamino)pyridines and alkenes were selectively transformed into the corresponding chiral amines with moderate to almost perfect enantiomeric excesses. Alkynes were also investigated as coupling partners. The effect of alkyl structure in substrates and directing groups were studied. This transformation represents the first example of a highly enantioselective C-H bond activation of a methylene group, not at allylic or benzylic position.

General and mild preparation of 2-aminopyridines

A general and facile one-pot amination procedure for the synthesis of 2-aminopyridines from the corresponding pyridine-N-oxides is presented as a mild alternative to SNAr chemistry. A variety of amines and heterocyclic-N-oxides participate effectively in this transformation which uses the phosphonium salt, PyBroP, as a means of substrate activation.