461-88-1 Usage
Chemical Properties
Light yellow Cryst
Uses
Different sources of media describe the Uses of 461-88-1 differently. You can refer to the following data:
1. 2,4-Pyridinediamine was studies for its interaction with cholinesterase inhibitors, neostigmine (N390010) and edrophonium (E336000) as a combined treatment for the restoration of muscle contraction. E
xperiments have shown the doses of neostigmine and edrophonium could be halved when they were combined with a small small amount of 2,4-pyridinediamine without apparent loss of antagonistic potency.
2. 2,4-Pyridinediamine was studies for its interaction with cholinesterase inhibitors, neostigmine (N390010) and edrophonium (E336000) as a combined treatment for the restoration of muscle contraction. Experiments have shown the doses of neostigmine and edrophonium could be halved when they were combined with a small small amount of 2,4-pyridinediamine without apparent loss of antagonistic potency.
Check Digit Verification of cas no
The CAS Registry Mumber 461-88-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,6 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 461-88:
(5*4)+(4*6)+(3*1)+(2*8)+(1*8)=71
71 % 10 = 1
So 461-88-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H7N3/c6-4-1-2-8-5(7)3-4/h1-3H,(H4,6,7,8)
461-88-1Relevant articles and documents
A One-step Synthesis of 2,4-Bis(sec-alkylamino)-6-halo-3-pyridinecarbonitriles
Metzger, Roland,Oberdoerfer, Juergen,Schwager, Carlos,Thielecke, Wilfried,Boldt, Peter
, p. 946 - 953 (2007/10/02)
The title compounds, e.g. 2a-c or 7, are obtained by reaction of malononitrile (1) with sec-alkylhalides/aluminium chloride (except the alkyl fluorides) at room temperature.From these the corresponding 2,4-bis(sec-alkylamino)pyridines may be conveniently prepared.With hydrogen bromide, 1 or its "dimer" 10 (R = H) 2,4-diamino-6-bromo-5-pyridinecarbonitrile (17) is formed.