46346-12-7

Basic information

• Product Name: Morpholine, 4-(2-phenylethyl)-
• CAS NO: 46346-12-7
• Molecular Formula: C12H17NO
• Molecular Weight: 191.273
• Mol File: 46346-12-7.mol
• Article Data: 34

Chemical Properties

• CAS DataBase Reference: Morpholine, 4-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-(2-phenylethyl)-(46346-12-7)
• EPA Substance Registry System: Morpholine, 4-(2-phenylethyl)-(46346-12-7)

Safety Data

• Hazardous Substances Data: 46346-12-7(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 17376-04-4 2-phenethyl iodide 
• 622-24-2 2-phenylethyl chloride 
• 103-63-9 1-phenyl-2-bromoethane 
• 3240-94-6 N-(2-chlorethyl)morpholine 
• 100-42-5 styrene 
• 60-12-8 2-phenylethanol 
• 100-52-7 benzaldehyde 
• 73183-34-3 bis(pinacol)diborane 
• 100-44-7 benzyl chloride 
• 36838-59-2 N-styrylmorpholine 
• 122-78-1 phenylacetaldehyde 
• 17123-83-0 N-(phenylacetyl)morpholine 
• 64-04-0 phenethylamine 

Downstream Products

• 1312343-49-9 2-benzyl-4-phenethylmorpholine 
• 7469-58-1 4-(3-nitro-phenacyl)-4-phenethyl-morpholinium; bromide 
• 6277-94-7 4-phenacyl-4-phenethyl-morpholinium; bromide 
• 6274-06-2 4-phenethyl-4-(4-phenyl-phenacyl)-morpholinium; bromide 

Relevant articles and documents

Mechanistic studies of ruthenium-catalyzed anti-Markovnikov hydroamination of vinylarenes: Intermediates and evidence for catalysis through π-arene complexes

Studies are described that reveal the steps of the anti-Markovnikov hydroamination of vinylarenes with alkylamines catalyzed by Ru(COD)(2-methylallyl)2, bis(diphenylphosphino)pentane, and TfOH. Treatment of the catalyst components with an exces

B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of: In situ -formed enamines

A highly efficient B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of in situ-formed enamines in the presence of water and pinacolborane was developed. Regioselective β-deuteration of tertiary amines was achieved with high chemo- and regioselectivity. D2O was used as a readily available and cheap source of deuterium. Mechanistic studies indicated that B(C6F5)3 could activate water to promote the protonation and reduction of enamines. This journal is

Photo-induced thiolate catalytic activation of inert Caryl-hetero bonds for radical borylation

Substantial effort is currently being devoted to obtaining photoredox catalysts with high redox power. Yet, it remains challenging to apply the currently established methods to the activation of bonds with high bond dissociation energy and to substrates with high reduction potentials. Herein, we introduce a novel photocatalytic strategy for the activation of inert substituted arenes for aryl borylation by using thiolate as a catalyst. This catalytic system exhibits strong reducing ability and engages non-activated Caryl–F, Caryl–X, Caryl–O, Caryl–N, and Caryl–S bonds in productive radical borylation reactions, thus expanding the available aryl radical precursor scope. Despite its high reducing power, the method has a broad substrate scope and good functional-group tolerance. Spectroscopic investigations and control experiments suggest the formation of a charge-transfer complex as the key step to activate the substrates.