465-78-1 Usage
Description
According to Poethke, this base does not occur naturally but is formed by loss ofmethylethylglycollic acid from Germerine (q.v.) during the extraction process.
Other workers, however, claim that it exists in Veratrum album and certain
species of Zygadenus. It forms glancing prisms from C6H6 and has [α]22D - 9°
(pyridine). It is only slightly soluble in most organic solvents. The hydrochloride
crystallizes from EtOH, m.p. 247-2500 C (dec.); the platinichloride decomposes
at 195-2000 C; picrate, yellow needles from Me2CO-Et20, decomposes at 244-
6°C and the triacetyl derivative has m.p. 242-4°C (dec.); [α]27D - 89° (pyridine).
Alkaline hydrolysis furnishes germine and (-)-methylethylacetic acid. The base
gives a cherry-red colour with H2S04 and a carmine-red colour with HCl, isobutyric acid being liberated from the latter mixture on heating.
References
Salzberger., Arch. Pharm., 228,462 (1890)
Poethke., ibid, 275,571 (1937)
Kupchan., J. Amer. Chem. Soc., 81, 1921 (1959)
Check Digit Verification of cas no
The CAS Registry Mumber 465-78-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,6 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 465-78:
(5*4)+(4*6)+(3*5)+(2*7)+(1*8)=81
81 % 10 = 1
So 465-78-1 is a valid CAS Registry Number.