46745-66-8

Basic information

• Product Name: 4-N-OCTYLSTYRENE
• Synonyms: P-OCTYL STYRENE;4-OCTYLSTYRENE;4-N-OCTYLSTYRENE;1-ethenyl-4-octylbenzene;benzene,1-ethenyl-4-octyl-;octylstyrene;p-octylvinylbenzene;styrene,4-octyl
• CAS NO: 46745-66-8
• Molecular Formula: C₁₆H₂₄
• Molecular Weight: 216.36
• Product Categories: monomer
• Mol File: 46745-66-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 114 °C / 1mmHg
• Flash Point: 136.525°C
• Appearance: /
• Density: 0.88
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.5100 to 1.5130
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-N-OCTYLSTYRENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-N-OCTYLSTYRENE(46745-66-8)
• EPA Substance Registry System: 4-N-OCTYLSTYRENE(46745-66-8)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 46745-66-8(Hazardous Substances Data)

Usage

Uses

4-n-Octylstyrene (stabilized with TBC) is a useful research chemical.

InChI:InChI=1/C16H24/c1-3-5-6-7-8-9-10-16-13-11-15(4-2)12-14-16/h4,11-14H,2-3,5-10H2,1H3

Upstream product

• 1779-49-3 Methyltriphenylphosphonium bromide 
• 49763-66-8 4-octylbenzaldehyde 
• 2189-60-8 Octylbenzene 
• 10541-56-7 4-n-octylacetophenone 

Downstream Products

• 6908-41-4 4-(methoxycarbonyl)benzyl alcohol 
• 162359-55-9 fingolimod 
• 177260-59-2 2-amino-4-(4-octylphenyl)butanol 
• 1430804-03-7 (2S,3S,4R)-4-amino-2-(4-octylphenethyl)tetrahydrofuran-3-ol 
• 876391-74-1 (2R)-2-(oxiranyl)-4-(4'-octylphenyl)butan-1-ol 
• 1430811-65-6 C₂₅H₄₄OSi 
• 1142015-13-1 (S)-FTY₇₂₀-ene-phosphonate 
• 1430811-63-4 C₂₁H₃₃NO₂ 
• 1430811-60-1 (S,E)-3-azido-3-(fluoromethyl)-5-(4-octylphenyl)pent-1-enylphosphonic acid 
• 1430811-59-8 (S,E)-3-amino-3-(fluoromethyl)-5-(4-octylphenyl)pent-1-enylphosphonic acid 
• 1430811-75-8 (S,E)-dimethyl 3-amino-3-(fluoromethyl)-5-(4-octylphenyl)pent-1-enylphosphonate 
• 1430811-74-7 (S,E)-dimethyl 3-azido-3-(fluoromethyl)-5-(4-octylphenyl)pent-1-enylphosphonate 
• 1430811-61-2 (S,E)-3-azido-3-(hydroxymethyl)-5-(4-octylphenyl)pent-1-enylphosphonic acid 
• 1142015-24-4 (S,E)-dimethyl 3-amino-3-(hydroxymethyl)-5-(4-octylphenyl)pent-1-enylphosphonate 

Relevant articles and documents

Synthesis of (S)-FTY720 vinylphosphonate analogues and evaluation of their potential as sphingosine kinase 1 inhibitors and activators

Sphingosine kinase 1 (SK1) is over-expressed in many cancers where it provides a selective growth and survival advantage to these cells. SK1 is thus a target for anti-cancer agents that can promote apoptosis of cancer cells. In previous work, we synthesized a novel allosteric SK1 inhibitor, (S)-FTY720 vinylphosphonate. We now report a more expeditious route to this inhibitor which features B-alkyl Suzuki coupling as a key step and show that replacement of the amino group in (S)-FTY720 vinylphosphonate with an azido group converts the vinylphosphonate from an allosteric inhibitor to an activator of SK1 at low micromolar concentrations. Our results demonstrate the feasibility of using the (S)-FTY720 vinylphosphonate scaffold to define structure-activity relationships in the allosteric site of SK1.

Polystyrene anion exchange polymer pharmaceutical composition

Polystyrene polymers having a quaternised ammonium group and their use in a method of treatment of hypercholesterolaemia. A particular compound of the invention is (N,N-dimethyl-N-dodecyl-ammoniomethylstyrene-ethyl methacrylate-divinylbenzene co-polymer,