471-15-8 Usage
Description
THUJONE is a naturally occurring monoterpene ketone found in the essential oils of various plants, including the common wormwood (Artemisia absinthium) and the essential oil of Pistacia vera L. It is known for its distinctive aroma and has been used in various applications due to its unique chemical properties.
Uses
Used in Organic Synthesis:
THUJONE is used as a reactant in organic synthesis for [application reason] the production of various chemical compounds and materials. Its unique chemical structure allows it to participate in a range of reactions, making it a valuable component in the synthesis of different products.
Used in Aromatherapy and Perfumery:
THUJONE is used as a fragrance component in the aromatherapy and perfumery industries for [application reason] its distinctive and pleasant aroma. It contributes to the overall scent profile of various perfumes and aromatic products, enhancing their appeal and effectiveness.
Used in Flavor and Food Industry:
THUJONE is used as a flavoring agent in the food and beverage industry for [application reason] its ability to add a unique taste and aroma to various products. It is often used in small quantities to provide a distinct flavor profile to certain types of food and beverages.
Used in Pharmaceutical Industry:
THUJONE is used as an active ingredient or a component in the pharmaceutical industry for [application reason] its potential therapeutic properties. It has been studied for its effects on the central nervous system and its potential use in the treatment of various conditions, although its use in this industry is subject to further research and regulation.
Used in Pesticides and Insect Repellents:
THUJONE is used as an active ingredient in pesticides and insect repellents for [application reason] its natural insecticidal properties. It can help control and repel various types of insects, making it a useful component in the development of eco-friendly and effective pest control solutions.
Check Digit Verification of cas no
The CAS Registry Mumber 471-15-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,7 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 471-15:
(5*4)+(4*7)+(3*1)+(2*1)+(1*5)=58
58 % 10 = 8
So 471-15-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H16O/c1-6(2)10-4-8(10)7(3)9(11)5-10/h6-8H,4-5H2,1-3H3/t7-,8+,10-/m0/s1
471-15-8Relevant articles and documents
A six-step total synthesis of α-thujone and: D 6-α-thujone, enabling facile access to isotopically labelled metabolites
Thamm, Irene,Richers, Johannes,Rychlik, Michael,Tiefenbacher, Konrad
, p. 11701 - 11703 (2016/10/04)
The short synthesis of α-thujone relies on the functionalization of the readily available dimethylfulvene. Furthermore, the three main metabolites of the natural product were also synthesized. Since d6-acetone can be used as a starting material, the route developed allows for the facile incorporation of isotopic labels which are required for detecting and quantifying trace amounts via GC/MS analysis.
(-) 3 Isothujone, a small nonnitrogenous molecule with antinociceptive activity in mice
Rice,Wilson
, p. 1054 - 1057 (2007/10/13)
(-) 3 isothujone and (+) 3 thujone were examined for antinociceptive activity using the hot plate and Nilsen tests. In the hot plate test (-) 3 isothujone (ED50 = 6.5 mg/kg) was found to be codeine like and equipotent with (-) Δ9 tetrahydrocannabinol while the racemic material was essentially half as potent as the levorotatory isomer. (+) 3 Thyjone was inactive in both antinociceptive tests as were several structural analogues of the 3 thujones. As with the THC's less antinociceptive activity was observed in the Nilsen test than in the hot plate assay. Acute toxicities for the 3 thujones were determined and vastly improved synthetic procedures have been developed for two long known but difficultly accessible 3 thujanols.
