473732-10-4

Basic information

• Product Name: 2-hydroxy-3-[(2-methoxy-3,4-dioxocyclobut-1-en-1-yl)amino]-N,N-dimethylbenzamide
• Synonyms: 2-Hydroxy-3-[(2-methoxy-3,4-dioxocyclobut-1-en-1-yl)amino]-N,N-dimethylbenzamide; benzamide, 2-hydroxy-3-[(2-methoxy-3,4-dioxo-1-cyclobuten-1-yl)amino]-N,N-dimethyl-
• CAS NO: 473732-10-4
• Molecular Formula: C₁₄H₁₄N₂O₅
• Molecular Weight: 290.2714
• Mol File: 473732-10-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 494.952°C at 760 mmHg
• Flash Point: 253.138°C
• Density: 1.426g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.629
• CAS DataBase Reference: 2-hydroxy-3-[(2-methoxy-3,4-dioxocyclobut-1-en-1-yl)amino]-N,N-dimethylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-3-[(2-methoxy-3,4-dioxocyclobut-1-en-1-yl)amino]-N,N-dimethylbenzamide(473732-10-4)
• EPA Substance Registry System: 2-hydroxy-3-[(2-methoxy-3,4-dioxocyclobut-1-en-1-yl)amino]-N,N-dimethylbenzamide(473732-10-4)

Safety Data

• Hazardous Substances Data: 473732-10-4(Hazardous Substances Data)

Upstream product

• 464913-11-9 3-amino-2-hydroxy-N,N-dimethylbenzamide 
• 5222-73-1 3,4-dimethoxy-3-cyclobutene-1,2-dione 
• 1000993-70-3 2-hydroxy-N,N-dimethyl-3-amino-benzamide hydrochloride 
• 85-38-1 3-nitrosalicylic acid 
• 66952-65-6 2-hydroxy-N,N-dimethyl-3-nitrobenzamide 

Downstream Products

• 473724-57-1 C₂₆H₃₆N₄O₅ 
• 473727-83-2 squaramide 

Relevant articles and documents

PROCESS FOR CONTROLLED CRYSTAL SIZE IN 1,2-SUBSTITUTED 3,4-DIOXO-1-CYCLOBUTENE COMPOUNDS

This application discloses a novel process for the preparation of 2-Hydroxy-N,N-dimethyl-3-[[2-[[1(R)-(5-methyl-2-furanyl)propyl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]benzamide, which has utility, for example, in the treatment of CXC chemokine-mediated diseases.

3,4-DI-SUBSTITUTED CYCLOBUTENE-1,2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel cyclobutenedione Compounds comprising a cycloclobutenedione ring, a substituted phenyl ring, and a -CH(C2H5)-furan moiety. The phenyl ring and the -CH(C2H5)-furan moiety are each bound to the

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.