473735-52-3

Basic information

• Product Name: 4-aminomethyl-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-aminomethyl-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 473735-52-3
• Molecular Weight: 416.302
• Mol File: 473735-52-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-aminomethyl-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-aminomethyl-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester(473735-52-3)
• EPA Substance Registry System: 4-aminomethyl-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester(473735-52-3)

Safety Data

• Hazardous Substances Data: 473735-52-3(Hazardous Substances Data)

Upstream product

• 473736-90-2 tert-butyl 4-cyano-4-(4-iodophenyl)piperidine-1-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 821-48-7 bis-(2-chloroethyl)amine hydrochloride 

Downstream Products

• 473737-14-3 4-(4-iodo-phenyl)-4-[(2,2,2-trifluoro-acetylamino)-methyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 473737-06-3 4-(4-iodo-phenyl)-4-(isobutoxycarbonylamino-methyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 473735-65-8 [4-(3'-cyano-biphenyl-4-yl)-1-cyclopropylmethyl-piperidin-4-ylmethyl]-carbamic acid isobutyl ester 
• 473737-03-0 4-[(3-chloro-4-fluoro-benzenesulfonylamino)-methyl]-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 473735-64-7 3-chloro-N-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopropylmethyl-piperidin-4-ylmethyl]-4-fluoro-benzenesulfonamide 
• 473736-97-9 4-{[2-(3,5-difluoro-phenyl)-acetylamino]-methyl}-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Aryl and biaryl piperidines with MCH modulatory activity

In one embodiment, this invention provides a novel class of compounds as antagonists of the MCH receptor, methods of preparing such compounds, pharmaceutical compositions containing one or more of the compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention or amelioration or one or more of diseases associated with the MCH receptor. An illustrative inventive compound is shown below: 1