477535-41-4

Basic information

• Product Name: 3-BROMO-5-(TRIFLUOROMETHYL)BENZALDEHYDE
• Synonyms: 3-BROMO-5-(TRIFLUOROMETHYL)BENZALDEHYDE;3-Bromo-5-(trifluoromethyl)benzaldehyde97%;1-Bromo-3-formyl-5-trifluoromethylbenzene;3-Bromo-5-formylbenzotrifluoride;3-Bromo-5-formylbenzotrifluoride, 5-Bromo-alpha,alpha,alpha-trifluoro-m-tolualdehyde;Benzaldehyde, 3-bromo-5-(trifluoromethyl)-
• CAS NO: 477535-41-4
• Molecular Formula: C₈H₄BrF₃O
• Molecular Weight: 253.02
• EINECS: 1592732-453-0
• Product Categories: Aldehydes;blocks;Bromides;Aromatic Aldehydes & Derivatives (substituted);Fluorine series
• Mol File: 477535-41-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 219℃
• Flash Point: 86℃
• Appearance: /
• Density: 1.677
• Vapor Pressure: 0.123mmHg at 25°C
• Refractive Index: 1.5110
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive: Air Sensitive
• CAS DataBase Reference: 3-BROMO-5-(TRIFLUOROMETHYL)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-5-(TRIFLUOROMETHYL)BENZALDEHYDE(477535-41-4)
• EPA Substance Registry System: 3-BROMO-5-(TRIFLUOROMETHYL)BENZALDEHYDE(477535-41-4)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-36-43
• Safety Statements: 26-36/37
• Hazardous Substances Data: 477535-41-4(Hazardous Substances Data)

Usage

General Description

3-Bromo-5-(trifluoromethyl)benzaldehyde is a chemical compound categorized under the class of organic compounds known as benzaldehydes. It is defined by a benzene ring bearing a single formyl group and functional groups like bromine and trifluoromethyl. 3-BROMO-5-(TRIFLUOROMETHYL)BENZALDEHYDE is notable for its industrial and scientific use, especially in the conduct of various chemical reactions. It's typically used in chemical synthesis, serving as a reagent or intermediate in the preparation of more complex chemical structures. Its physical characteristics may include a characteristic smell (as many aromatic aldehydes do), and its specifications can vary based on the requirements of the specific application.

InChI:InChI=1/C8H4BrF3O/c9-7-2-5(4-13)1-6(3-7)8(10,11)12/h1-4H

Upstream product

• 172023-97-1 (3‐bromo‐5‐(trifluoromethyl)phenyl)methanol 
• 401-84-3 1,3-dibromo-5-(trifluoromethyl)benzene 
• 68-12-2 N,N-dimethyl-formamide 
• 958258-15-6 3-bromo-5-(trifluoromethyl)benzoyl chloride 
• 880652-44-8 3-bromo-N-methoxy-N-methyl-5-(trifluoromethyl)benzamide 
• 328-67-6 3-bromo-5-(trifluoromethyl)benzoic acid 
• 626-41-5 3,5-dibromophenol 

Downstream Products

• 1257310-68-1 (3-formyl-5-trifluoromethylphenyl)carbamic acid 2-trimethylsilanylethyl ester 
• 1237536-11-6 3-(1-methyl-1H-pyrazol-4-yl)-5-(trifluoromethyl)benzoic acid 
• 954124-06-2 1-[3-bromo-5-(trifluoromethyl)phenyl]ethanol 
• 1541197-82-3 2-(3-bromo-5-(trifluoromethyl)phenyl)-[1,3]dioxolane 
• 1541197-80-1 3-amino-3-[3-(1-hydroxy-1-methylethyl)-5-(trifluoromethyl)phenyl]propionic acid ethyl ester hydrochloride salt 
• 1541197-86-7 3-(1-hydroxy-1-methylethyl)-5-trifluoromethylbenzaldehyde 
• 1541197-84-5 2-(3-trifluoromethyl-5-[1,3]dioxolan-2-ylphenyl)propan-2-ol 
• 1541197-12-9 (3S)-3-(2-(3-hydroxy-5-((5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino)benzamido)acetamido)-3-(3-(2-hydroxypropan-2-yl)-5-(trifluoromethyl)phenyl)propanoic acid 
• 1541199-09-0 (3S)-ethyl 3-(2-(3-hydroxy-5-((5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino)benzamido)acetamido)-3-(3-(2-hydroxypropan-2-yl)-5-(trifluoromethyl)phenyl)propanoate 
• 1541199-08-9 (S)-ethyl 3-amino-3-(3-trifluoromethyl-5-(2-hydroxypropan-2-yl)phenyl)propionate hydrochloride 
• 1541199-06-7 (S)-3-amino-3-(3-(2-hydroxypropan-2-yl)-5-(trifluoromethyl)phenyl)propanoic acid 
• 1453069-80-1 (S)-N-(3-bromo-5-(trifluoromethyl)benzylidene)-2-methylpropane-2-sulfinamide 
• 1453069-28-7 (1S,8aS)-7,7-bis(2-hydroxyethyl)-N-((R)-1-(3-isopropyl-5-(trifluoromethyl)phenyl)ethyl)-N-methyl-6-oxo-1-o-tolylhexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxamide 
• 1453069-27-6 (1S,8aS)-N-((R)-1-(3-isopropyl-5-(trifluoromethyl)phenyl)ethyl)-N-methyl-6-oxo-1-o-tolylhexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxamide 

Relevant articles and documents

GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES

This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates. The diboron compounds are characterized by formula (I), which is: R1-X-R2, and wherein "X" is a mono- to multiatomic linker and where R1 and R2, which may be identical or different, each represents a group of Formula (lla) or (IIb) Also described are diboron conjugates represented by the general Formula (I'), which is: R1'-X'-R2', in which either the moeities R1' or R2' or X' carry a drug that is covalently attached to the diboron compound.

DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES

The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specification, which has a superior RBP4-lowering action and is useful as a pharmaceutical composition for the prophylaxis or treatment of a disease or condition mediated by an increase in RBP4.

CETP INHIBITORS

Compounds of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formu