478263-90-0

Basic information

• Product Name: Benzoic acid, 5-fluoro-2-[(8-quinolinylsulfonyl)amino]-
• CAS NO: 478263-90-0
• Molecular Formula: C16H11FN2O4S
• Molecular Weight: 346.339
• Mol File: 478263-90-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 5-fluoro-2-[(8-quinolinylsulfonyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 5-fluoro-2-[(8-quinolinylsulfonyl)amino]-(478263-90-0)
• EPA Substance Registry System: Benzoic acid, 5-fluoro-2-[(8-quinolinylsulfonyl)amino]-(478263-90-0)

Safety Data

• Hazardous Substances Data: 478263-90-0(Hazardous Substances Data)

Upstream product

• 18704-37-5 quinoline-8-sulfonyl chloride 
• 446-08-2 2-amino-5-fluorobenzoic acid 

Downstream Products

• 478263-53-5 (S)-5-fluoro-2-(quinoline-8-sulfonylamino)-N-(1-phenyl-propyl)benzamide 

Relevant articles and documents

Kv1.5-BLOCKER FOR THE SELECTIVE INCREASE OF ATRIAL CONTRACTILITY AND TREATMENT OF CARDIAC INSUFFICIENCY

The invention relates to the atrial contractility-increasing effect of Kv1.5 blockers, especially phenylcarboxamides of the formulae Ia or Ib or pharmaceutically acceptable salts thereof, for treating reduced atrial contractility and heart failure, e

Combination of phenylcarboxylic acid amides with beta-adrenoreceptor blockers and their use for the treatment of atrial arrhythmias

The invention relates to the combination of one or more beta-blockers and of one or more Kv1.5 blockers, in particular phenylcarboxamides of the formula la and/or lb and/or physiologically tolerable salts thereof, and the use of the combination for the treatment or prophylaxis of atrial arrhythmias.