478963-06-3

Basic information

• Product Name: 2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-4-(pyridin-3-ylmethylsulfanyl)-butyric acid
• Synonyms: 2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-4-(pyridin-3-ylmethylsulfanyl)-butyric acid
• CAS NO: 478963-06-3
• Molecular Weight: 452.596
• Mol File: 478963-06-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-4-(pyridin-3-ylmethylsulfanyl)-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-4-(pyridin-3-ylmethylsulfanyl)-butyric acid(478963-06-3)
• EPA Substance Registry System: 2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-4-(pyridin-3-ylmethylsulfanyl)-butyric acid(478963-06-3)

Safety Data

• Hazardous Substances Data: 478963-06-3(Hazardous Substances Data)

Upstream product

• 257933-87-2 N-isobutyl-4-methoxy-N-(2-oxo-tetrahydro-thiophen-3-yl)-benzenesulfonamide 
• 69966-55-8 3-picolyl bromide 
• 478957-90-3 2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-4-(pyridin-3-ylmethylsulfanyl)-butyric acid methyl ester 

Downstream Products

• 478964-55-5 2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-4-(pyridin-3-ylmethylsulfanyl)-N-trityloxy-butyramide 

Relevant articles and documents

N-aryl sulfonyl homocysteine hydroxamate inhibitors of matrix metalloproteinases: Further probing of the S1, S1′, and S2′ pockets

A series of N-arylsulfonyl S-alkyl homocysteine hydroxamic acids were synthesized with variations in three subsites corresponding to P1, P1′, and P2′. Enzyme assays with a variety of MMPs revealed activity at the low nanomolar level.