4794-82-5

Basic information

• Product Name: 1H-Imidazol-2-amine, 4,5-dihydro-N-(4-methylphenyl)-
• CAS NO: 4794-82-5
• Molecular Formula: C10H13N3
• Molecular Weight: 175.233
• Mol File: 4794-82-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-Imidazol-2-amine, 4,5-dihydro-N-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazol-2-amine, 4,5-dihydro-N-(4-methylphenyl)-(4794-82-5)
• EPA Substance Registry System: 1H-Imidazol-2-amine, 4,5-dihydro-N-(4-methylphenyl)-(4794-82-5)

Safety Data

• Hazardous Substances Data: 4794-82-5(Hazardous Substances Data)

Usage

Class of compound

Imidazole derivative

Structure

1H-Imidazol-2-amine, 4,5-dihydro with a substituted amine group and a 4-methylphenyl group

Usage

Synthesis of pharmaceuticals

Biological activity

Potential biological activity

Importance

Building block in the development of medicinal and chemical compounds.

Upstream product

• 5464-11-9 2-methylthio-2-imidazoline hydroiodide 
• 106-49-0 p-toluidine 
• 20112-79-2 2-methylthioimidazoline 
• 622-59-3 1-isothiocyanato-4-methylbenzene 
• 13037-22-4 methyl (N-(4-methylphenyl))dithiocarbamate 
• 726-42-1 di-p-tolylcarbodiimide 
• 107-15-3 ethylenediamine 
• 2327-67-5 N-(p-tolyl)-P,P,P-triphenylphosphine imide 
• 2101-86-2 p-methylazidobenzene 
• 865075-68-9 N-[bis(1H-benzotriazol-1-yl)methylidene]-4-methylaniline 
• 33141-99-0 dimethyl N-(4-methylphenyl)dithioimidocarbonate 

Relevant articles and documents

Ti-amide catalyzed synthesis of cyclic guanidines from di-/triamines and carbodiimides

A titanacarborane monoamide catalyzed, one-step synthesis of mono/bicyclic guanidines from commercially available di/triamines and carbodiimides is reported. The reaction mechanism is also proposed.

The preparation of 1,2,3-trisubstituted guanidines

An operationally straightforward and efficient benzotriazole-based method for the guanylation of diverse amines by use of the new reagent classes (bis-benzotriazol-1-yl-methylene)amines 13a-13f and benzotriazole-1- carboxamidines 17a-17i is described. The preparation is described for a variety of both acyclic and cyclic 1,2,3-trisubstituted guanidines in high yields.

Synthesis of 2-Aryliminoimidazolidines and 2-Arylaminobenzimidazoles from Methyl N-Aryldithiocarbamates

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