483349-31-1

Basic information

• Product Name: 5-allylamino-1-(chloromethyl)-3-[(2E)-3-(4-methoxyphenyl)-2-propenoyl]-1,2-dihydro-3H-benzo[e]indole
• Synonyms: 5-allylamino-1-(chloromethyl)-3-[(2E)-3-(4-methoxyphenyl)-2-propenoyl]-1,2-dihydro-3H-benzo[e]indole
• CAS NO: 483349-31-1
• Molecular Weight: 432.95
• Mol File: 483349-31-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-allylamino-1-(chloromethyl)-3-[(2E)-3-(4-methoxyphenyl)-2-propenoyl]-1,2-dihydro-3H-benzo[e]indole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-allylamino-1-(chloromethyl)-3-[(2E)-3-(4-methoxyphenyl)-2-propenoyl]-1,2-dihydro-3H-benzo[e]indole(483349-31-1)
• EPA Substance Registry System: 5-allylamino-1-(chloromethyl)-3-[(2E)-3-(4-methoxyphenyl)-2-propenoyl]-1,2-dihydro-3H-benzo[e]indole(483349-31-1)

Safety Data

• Hazardous Substances Data: 483349-31-1(Hazardous Substances Data)

Upstream product

• 830-09-1 3-(4'-methoxyphenyl)propenoic acid 
• 483349-29-7 5-[allyl(tert-butyloxycarbonyl)amino]-3-(tert-butyloxycarbonyl)-1-(chloromethyl)-1,2-dihydro-3H-benzo[e]indole 
• 24824-28-0 naphthalene-1,3-diamine 
• 4112-02-1 1-iodo-2,4-dinitronaphthalene 
• 605-69-6 1-hydroxy-2,4-dinitronaphthalene 
• 943-89-5 (E)-3-(4-methoxyphenyl)acrylic acid 
• 1017279-61-6 allyl-(1-chloromethyl-2,3-dihydro-1H-benzo[e]indol-5-yl)-amine 
• 483349-27-5 5-(allyl(tert-butoxycarbonyl)amino)-1-((2,2,6,6-tetramethyl-piperidin-1-yloxy)methyl)-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester 
• 483349-28-6 5-[allyl(tert-butyloxycarbonyl)amino]-3-(tert-butyloxacarbonyl)-1-(hydroxymethyl)-1,2-dihydro-3H-benzo[e]indole 
• 483349-25-3 (4-(tert-butoxycarbonylamino)-1-iodo-naphthalen-2-yl)carbamic acid tert-butyl ester 
• 161393-72-2 1,3-dinitronaphthalen-4-yl trifluoromethanesulfonate 
• 483349-26-4 allyl-[3-(allyl-tert-butoxycarbonyl-amino)-4-iodo-naphthalen-1-yl]-carbamic acid tert-butyl ester 

Downstream Products

• 204915-94-6 {1-chloromethyl-3-[3-(4-methoxy-phenyl)acryloyl]-2,3-dihydro-1H-benzo[e]indol-5-yl}-carbamic acid tert-butyl ester 
• 204915-50-4 (2E)-1-[5-amino-1-(chloromethyl)-1H,2H,3H-benzo[e]indol-3-yl]-3-(4-methoxyphenyl)prop-2-en-1-one 

Relevant articles and documents

A new short synthesis of 3-substituted 5-Amino-1-(chloromethyl)-1,2-dihydro-3H-benzo[e]indoles (Amino-CBIs)

A new short synthesis of 3-substituted 5-amino-1-(chloromethyl)-1,2-dihydro-3H-benzo[e]indoles from Martius Yellow is disclosed. The key steps of the synthesis were three efficient regioselective reactions (iodination, 5-exo-trig aryl radical-alkene cyclization and carboxylation).