484-33-3 Usage
General Description
Pongamol is a naturally occurring chemical compound found in the seeds and oil of the Pongamia pinnata tree. It is classified as a flavonoid and is known for its antioxidant, anti-inflammatory, and antimicrobial properties. Pongamol has been studied for its potential use in skincare products for its ability to protect the skin from UV radiation and environmental damage. Additionally, it has shown promise in the treatment of various skin conditions such as acne, eczema, and psoriasis due to its anti-inflammatory and antimicrobial effects. Research also suggests that Pongamol may have potential as a natural insecticide and in the treatment of certain types of cancer. Overall, Pongamol is a versatile and beneficial compound with a wide range of potential applications in skincare, medicine, and agriculture.
Check Digit Verification of cas no
The CAS Registry Mumber 484-33-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 4 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 484-33:
(5*4)+(4*8)+(3*4)+(2*3)+(1*3)=73
73 % 10 = 3
So 484-33-3 is a valid CAS Registry Number.
InChI:InChI=1/C18H14O4/c1-21-18-13(7-8-17-14(18)9-10-22-17)16(20)11-15(19)12-5-3-2-4-6-12/h2-11,19H,1H3/b15-11-
484-33-3Relevant articles and documents
Preparation method and application of pongamol
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Paragraph 0008; 0089; 0098-0099, (2019/10/01)
The invention belongs to the field of medicinal chemistry, and relates to a preparation method and application of pongamol. The preparation method comprises the following steps: with 1,3-cyclohexanedione (6) as a starting raw material, carrying out a cyclization reaction to obtain 6,7-dihydro-4-(5H)-benzofuranone (7); carrying out acylation reaction on the compound (7) to obtain 5-acetyl-6,7-dihydro-4-(5H)-benzofuranone (8); carrying out dehydrogenation reaction on the compound (8) to obtain 1-(4-hydroxy-5-benzofuryl) ethyl ketone (3); carrying out methylation reaction on the compound (3) to obtain 1-(4-methoxy-5-benzofuryl) ethyl ketone (4); and condensing the compound (4) with benzoyl chloride to obtain the pongamol. According to the preparation method, the selected reagents are cheap and easy to obtain, the post-treatment method is simple, the reaction conditions are mild, and the product yield is high. Pharmacological activity experiments show that the synthesized compound has nerve injury resistance and anti-inflammatory activity, which means that the compound has a good application prospect in the field of treatment of nerve injury and inflammation related diseases.