4874-65-1

Basic information

• Product Name: Cyclopentanecarboxamide, 2-oxo-N-phenyl-
• CAS NO: 4874-65-1
• Molecular Formula: C12H13NO2
• Molecular Weight: 203.241
• Mol File: 4874-65-1.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Cyclopentanecarboxamide, 2-oxo-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxamide, 2-oxo-N-phenyl-(4874-65-1)
• EPA Substance Registry System: Cyclopentanecarboxamide, 2-oxo-N-phenyl-(4874-65-1)

Safety Data

• Hazardous Substances Data: 4874-65-1(Hazardous Substances Data)

Upstream product

• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 62-53-3 aniline 
• 15370-12-4 3-phenyl-6,7-dihydro-5H-cyclopenta[e][1,3]oxazine-2,4-dione 
• 1460-08-8 2-diazocyclohexane-1,3-dione 
• 32961-64-1 4,5,6,7-tetrahydrocyclopenta-1,3-dioxin-4-one 
• 50882-16-1 2-oxocyclopentane-1-carboxylic acid 
• 120-92-3 cyclopentanone 
• 10472-24-9 methyl 2-oxocyclopentane-1-carboxylate 
• 765-87-7 cyclohexane-1,2-dione 
• 622-37-7 Phenyl azide 
• 622-16-2 1,3-Diphenylcarbodiimide 
• 103-71-9 phenyl isocyanate 
• 61387-05-1 3-phenyl-2-phenylimino-2,3,6,7-tetrahydro-5H-cyclopenta[e][1,3]oxazin-4-one 
• 936-52-7 1-(N-morpholino)cyclopent-1-ene 

Downstream Products

• 4874-57-1 N-phenyl-2-(phenylamino)cyclopent-1-ene-1-carboxamide 

Relevant articles and documents

From Simple Cyclic 1,3-Ketoamides to Complex Spirolactams by Supported Heterogeneous Organocatalysis with PS-BEMP

The reaction between cyclic 1,3-ketoamides and Michael acceptors in the presence of a catalytic amount of a polymer-supported organobase PS-BEMP has been developed for a direct access to spirocyclic 1,3-ketolactams through a domino Michael addition/hemiac

Highly Selective Difluoromethylations of β-Keto Amides with -TMSCF 2Br under Mild Conditions

Without employing any transition metal and other additives, efficient methods for selective difluoromethylations of β-keto amides with TMSCF 2 Br reagent have been developed under mild conditions. This protocol allows a convenient access to various α-difluoromethyl β-keto amides with excellent yields (up to 93%) and high carbon/oxygen (C/O) regioselectivities (up to 99:1). The C/O selectivity of β-keto amides could be easily reversed and controlled by simply changing the base. This protocol can be easily scaled-up and the C-difluoromethylation product could be reduced into CF 2 H-containing amino alcohol derivatives. Moreover, the first enantioselective electrophilic difluoromethylation of β-keto amides has been achieved by phase-transfer catalysis.

Eco-friendly access to β-ketoamides: One-step catalyst-and solvent-free amidation of β-ketoesters under microwave irradiation

A highly efficient and facile catalyst- and solvent-free one step amidation of β-ketoesters, without using any additional reagents, is described. Therefore, β-ketoamides are obtained in good to excellent yields by condensation of β-ketoesters with various primary or secondary amines. This eco-friendly protocol has been developed under microwave irradiation.