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492-34-2

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492-34-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 492-34-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 2 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 492-34:
(5*4)+(4*9)+(3*2)+(2*3)+(1*4)=72
72 % 10 = 2
So 492-34-2 is a valid CAS Registry Number.

492-34-2Relevant articles and documents

Five new pregnane glycosides from Gymnema sylvestre and their α-glucosidase and &alphla;-amylase inhibitory activities

Kim, Seung Hyun,Kim, Sun Yeou,Lee, Jae Hyuk,Ngoc, Tran Minh,Nhiem, Nguyen Xuan,Park, Seon Ju,Tai, Bui Huu,Trang, Do Thi,Van Hung, Nguyen,Van Kiem, Phan,Van Minh, Chau,Yen, Duong Thi Hai,Yen, Pham Hai

, (2020/07/09)

Gymnema sylvestre, a medicinal plant, has been used in Indian ayurvedic traditional medicine for the treatment of diabetes. Phytochemical investigation of Gymnema sylvestre led to the isolation of five new pregnane glycosides, gymsylosides A-E (1-5) and four known oleanane saponins, 3β-O-β-D-glucopyranosyl (1→6)-β-D-glucopyranosyl oleanolic acid 28-O-β-D-glucopyranosyl ester (6), gymnemoside-W1 (7), 3β-O-β-D-xylopyranosyl-(1→6)-β-Dglucopyranosyl-(1→6)-β-D-glucopyranosyl oleanolic acid 28-O-β-D-glucopyranosyl ester (8), and alternoside XIX (9). Their structures were identified based on spectroscopic evidence and comparison with those reported in the literature. All compounds were evaluated for their α-glucosidase and α-amylase inhibitory activities. Compounds 2-4 showed significant α-amylase inhibitory activity, with IC50 values ranging from 113.0 to 176.2 μM.

Two new polyhydroxypregnane glycosides from the roots of Cynanchum otophyllum

Shi, Lin-Mei,Liu, Wen-Hong,Yu, Qing,Wan, Hai-Tong

, p. 404 - 405 (2013/09/12)

Two new polyhydroxypregnane glycosides, namely cynotophyllosides I-J, were isolated from the roots of Cynanchum otophyllum, together with three known steroids, namely deacetylmetaplexigenin, sarcostin and hemoside. Their structures were established by ext

Cynanauriculoside C-E, three new antidepressant pregnane glycosides from Cynanchum auriculatum

Yang, Qing-Xiong,Ge, Yong-Chang,Huang, Xiao-Yan,Sun, Qian-Yun

experimental part, p. 170 - 175 (2012/05/04)

Based on the bioactive screening results, three new pregnane glycosides named as cynanauriculoside C-E (1-3), were isolated from the roots of Cynanchum auriculatum Royle ex Wight (Asclepiadaceae), together with two known ones, otophylloside L (4) and cynauricuoside C (5). On the basis of detailed spectroscopic analysis and chemical method, the structures of new compounds were characterized to be qingyangshengenin 3-O-β-d-oleandropyranosyl-(1 → 4)-β-d-cymaropyranoside (1), qingyangshengenin 3-O-β-d-glucopyranosyl- (1 → 4)-β-d-glucopyranosyl-(1 → 4) -α-l-cymaropyranosyl-(1 → 4)-β-d-oleandropyranosyl-(1 → 4)-β-d-cymaropyranoside (2) and caudatin 3-O-β-d-glucopyranosyl-(1 → 4)-β-d-glucopyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-oleandropyranosyl-(1 → 4)-β-d-digitoxopyranoside (3). In the despair mice models, these pregnane glycosides showed significant antidepressant activity at the dosage of 50 mg/kg (i.g.). The most potent one was cyanauriculatoisde D (2), which was close to the positive control fluoxetine (20 mg/kg).

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