492-94-4

Basic information

• Product Name: Furil
• Synonyms: di-2-furanyl-ethanedion;di-2-furanylethanedione;Di-2-furylglyoxal;Difuranylglyoxal;Difuroyl;ALPHA-FURIL;2,2'-FURIL;1,2-DI(2-FURYL)ETHANE-1,2-DIONE
• CAS NO: 492-94-4
• Molecular Formula: C₁₀H₆O₄
• Molecular Weight: 190.15
• EINECS: 207-766-7
• Product Categories: Building Blocks;Furans;Heterocyclic Building Blocks
• Mol File: 492-94-4.mol
• Article Data: 98

Chemical Properties

• Melting Point: 163-165 °C(lit.)
• Boiling Point: 245.64°C (rough estimate)
• Flash Point: 138.4ºC
• Appearance: White crystal or powder. Odorless.
• Density: 1.1083 (rough estimate)
• Vapor Pressure: 0.000971mmHg at 25°C
• Refractive Index: 1.4440 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• BRN: 383882
• CAS DataBase Reference: Furil(CAS DataBase Reference)
• NIST Chemistry Reference: Furil(492-94-4)
• EPA Substance Registry System: Furil(492-94-4)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: LV0580000
• TSCA: Yes
• HazardClass: IRRITANT
• Hazardous Substances Data: 492-94-4(Hazardous Substances Data)

Usage

Description

Furil, also known as 2,5-dihydrofuran, is an organic compound with the chemical formula C4H4O2. It is a yellow-brown crystalline powder that undergoes catalytic asymmetric transfer hydrogenation to yield hydrofuroin. Furil is a versatile compound with various applications across different industries.

Uses

Used in Chemical Synthesis:
Furil is used as a key intermediate in the synthesis of various organic compounds, particularly in the preparation of dioxomolybdenum(VI) complexes in situ. This application is crucial for the development of new materials and chemicals with specific properties and functions.
Used in Pharmaceutical Industry:
Furil serves as a building block for the synthesis of pharmaceutical compounds. Its unique structure allows for the creation of new drugs with potential therapeutic applications, contributing to the advancement of medical treatments.
Used in Material Science:
In the field of material science, Furil can be utilized in the development of novel materials with specific properties, such as improved strength, flexibility, or chemical resistance. Its versatility in chemical reactions enables the creation of new polymers and composites with tailored characteristics for various applications.
Used in Research and Development:
Furil is also used as a research compound in academic and industrial laboratories. Its unique chemical properties make it an interesting subject for studying reaction mechanisms, exploring new synthetic routes, and understanding the fundamental principles of organic chemistry.

Purification Methods

Furil crystallises from MeOH or *benzene (charcoal). [Beilstein 19 III/IV 2008.]

InChI:InChI=1/C10H6O4/c11-9(7-3-1-5-13-7)10(12)8-4-2-6-14-8/h1-6H

Upstream product

• 552-86-3 furoin 
• 527-69-5 2-furancarbonyl chloride 
• 930-68-7 cyclohexenone 
• 80671-28-9 furan-2-yl(trimethylsilyl)methanone 
• 930-30-3 cyclopent-2-enone 
• 2786-02-9 2-lithiofuran 
• 106675-70-1 N¹,N²-dimethoxy-N¹,N²-dimethyloxalamide 
• 98-01-1 furfural 
• 26324-60-7 1,2-bis(2-furyl)-2-trimethylsilanyloxyethanone 
• 3839-31-4 dimethyl(phenyl)silyllithium 
• 7553-56-2 iodine 
• 124-41-4 sodium methylate 
• 6047-91-2 2-furoyl cyanide 
• 144223-33-6 2-furoyl-1H-1,2,3-benzotriazole 

Downstream Products

• 69467-09-0 3-methylsulfanyl-5,6-bis(furan-2-yl)-1,2,4-triazine 
• 90358-65-9 5,6-di(furan-2-yl)-3-(pyridine-2-yl)-1,2,4-triazine 
• 121113-09-5 (4-Chloro-phenyl)-(4,5-di-furan-2-yl-1H-imidazol-2-yl)-methanone 
• 128371-15-3 methyl β-2-furyl-γ-oxo-2-furancrotonate 
• 791-28-6 Triphenylphosphine oxide 
• 128371-17-5 benzoyl β-2-furyl-γ-oxo-2-furanilidene 
• 128371-16-4 ethyl β-2-furyl-γ-oxo-2-furancrotonate 
• 36145-03-6 [2,2'-bipyridine]-3,3'-diol 
• 552-86-3 furoin 
• 105863-01-2 diphenyl-acetic acid dodecahydro-dipyrido[1,2-a;2',1'-c]pyrazine-1,12-diyl ester 
• 103443-72-7 1,12-bis-benzoyloxy-dodecahydro-dipyrido[1,2-a;2',1'-c]pyrazine 
• 88-14-2 2-furanoic acid 
• 105031-23-0 ((C₄H₃O)2(CO)2)B(C₆H₅)2 
• 1095200-47-7 2,3-di(furan-2-yl)-6-phenylquinoxaline 

Relevant articles and documents

Paramagnetic mononuclear oxovanadium(IV) complex as oxidation catalyst

2-Thiophenecarbanicotinic hydrazone is added with equimolar mixture of vanadyl acetyl acetonate in methanol to obtain oxovanadium(IV) complex of 2-thiophenecarbanicotinic hydrazone. Oxovanadium(IV) complex of 2-thiophenecarbanicotinic hydrazone is acted as an effective catalyst in the process. The catalytic reactions were carried under room temperature. The products generated were benzil and furil. The influence of solvent, oxidant and quantity of catalyst has been investigated. Oxovanadium(IV) complex of 2-thiophenecarba-nicotinic hydrazone proves significantly higher catalytic activity towards oxidation of secondary alcohols to ketones. The catalyst was proved to be very effective due to its recovery by simple filteration after completion of the reaction. It was reused several times which suggests that there is no change in the catalytic efficiency. Oxovanadium(IV) complex of 2-thiophenecarbanicotinic hydrazone did not show any leaching during the reaction, confirmed the heterogeneous nature.

Upgrading biogenic furans: Blended C10-C12 platform chemicals via lyase-catalyzed carboligations and formation of novel C12 - Choline chloride-based deep-eutectic-solvents

Benzaldehyde lyase (BAL) results in an efficient biocatalyst for the umpolung carboligation of furfural, HMF, and mixtures of them, leading to blended C10-C12 platform chemicals. Subsequently, the mixing and gentle heating (100°C) of the formed hydroxy-ketone with choline chloride leads to the formation of a novel biomass-derived deep-eutectic-solvent.

One-pot synthesis, structural analysis, and oxidation applications of a series of diaryltellurium dicarboxylates

This paper presents a concise and efficient one-pot synthesis of a variety of functionalized diaryltellurium dicarboxylates. The method is based on a mild photosensitized oxygenation of cheap and readily available carboxylic acids. The molecular structures of the diaryltellurium dicarboxylates were determined unambiguously using single-crystal X-ray diffraction analysis. The thus obtained diaryltellurium dicarboxylates were used to study the oxidation of benzoin derivatives.

Synthetic method for 1,2-diketone

The invention relates to the field of novel materials of fine chemicals, and especially relates to a novel technology for preparing 1,2-diketone compounds by using acyl halides which are simple and easy to obtain and by performing direct condensation coupling under promotion of a metal. Corresponding chemical reaction equations are shown in the description.