495-78-3 Usage
Description
3-(2-Hydroxyphenyl)propionic acid, a phenyl propionic acid derivative, is a monocarboxylic acid with a unique structure that features a 2-hydroxyphenyl group substituted at the 3rd position of propionic acid. It has been identified as a constituent in Justicia pectoralis Jacq. extract and has been studied for its various biological activities, including antiulcerogenic effects and microbial metabolism of catechin stereoisomers. Crystal structure analysis reveals that its crystals are monoclinic with a space group of P21/c.
Uses
Used in Pharmaceutical Industry:
3-(2-Hydroxyphenyl)propionic acid is used as a growth substrate for various strains of E. coli, which is essential for the study and development of new pharmaceutical compounds and understanding the metabolic pathways of these bacteria.
Used in Biomedical Research:
3-(2-Hydroxyphenyl)propionic acid serves as a standard in the study of microbial metabolism of catechin stereoisomers, which is crucial for understanding the bioavailability and health benefits of these compounds in the human body.
Used in Microbiology:
As a growth substrate for E. coli strains, 3-(2-Hydroxyphenyl)propionic acid is used to support the growth and maintenance of these bacteria in laboratory settings, allowing researchers to study their metabolic processes and potential applications in various fields.
Used in Chemical Analysis:
The crystal structure of 3-(2-Hydroxyphenyl)propionic acid, with its monoclinic form and P21/c space group, provides valuable information for researchers in the field of chemical analysis, particularly in understanding the structural properties of similar compounds and their potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 495-78-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 495-78:
(5*4)+(4*9)+(3*5)+(2*7)+(1*8)=93
93 % 10 = 3
So 495-78-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O3/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-4,10H,5-6H2,(H,11,12)/p-1
495-78-3Relevant articles and documents
Macroporous silica microcapsules immobilizing esterase with high hydrolysis reactivity
Fujiwara, Masahiro,Shoji, Shigeru,Murakami, Yuka,Ishikawa, Kazuhiko
, p. 1043 - 1045 (2020)
An esterase, 3,4-dihydrocoumarin hydrolase, was directly immobilized into silica microcapsules. The hydrolysis reaction of 3,4-dihydrocoumarin by a macroporous silica microcapsule immobilizing the esterase was faster than those by mesoporous ones. Using t
Ruthenium-catalyzed intramolecular arene C(sp2)-H amidation for synthesis of 3,4-dihydroquinolin-2(1 H)-ones
Au, Chi-Ming,Ling, Cho-Hon,Sun, Wenlong,Yu, Wing-Yiu
, p. 3310 - 3314 (2021/05/29)
We report the [Ru(p-cymene)(l-proline)Cl] ([Ru1])-catalyzed cyclization of 1,4,2-dioxazol-5-ones to form dihydroquinoline-2-ones in excellent yields with excellent regioselectivity via a formal intramolecular arene C(sp2)-H amidation. The reactions of the 2- and 4-substituted aryl dioxazolones proceeds initially through spirolactamization via electrophilic amidation at the arene site, which is para or ortho to the substituent. A Hammett correlation study showed that the spirolactamization is likely to occur by electrophilic nitrenoid attack at the arene, which is characterized by a negative ρ value of -0.73.
Pd nanoparticles on reverse phase silica gel as recyclable catalyst for Suzuki-Miyaura cross coupling reaction and hydrogenation in water
Shabbir, Saira,Lee, Sinyoung,Lim, Minkyung,Lee, Heejin,Ko, Hyeji,Lee, Youngbok,Rhee, Hakjune
, p. 296 - 304 (2017/07/12)
Two catalytic systems, consisting of palladium nanoparticles supported by reverse phase amino functionalized silica are utilized as catalysts for Suzuki-Miyaura reaction and hydrogenation in water. The catalysts were developed by modifying silica into bidentate ligands, using either 2-pyridinecarboxaldehyde or 2,2′-bipyridine-4,4′-dicarboxylic acid. The synthesized catalysts showed quantitative reaction yields and recyclability with negligible leaching of Pd nanoparticles. Various characterization techniques including XPS, ICP-MS, SEM, BET, XRD, TEM, 1H- and 13C- NMR are used to verify the efficiency of the catalysts.
