49571-47-3

Basic information

• Product Name: Thiocyanic acid, (1Z)-3-oxo-1-phenyl-1-propenyl ester
• CAS NO: 49571-47-3
• Molecular Formula: C10H7NOS
• Molecular Weight: 189.238
• Mol File: 49571-47-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Thiocyanic acid, (1Z)-3-oxo-1-phenyl-1-propenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Thiocyanic acid, (1Z)-3-oxo-1-phenyl-1-propenyl ester(49571-47-3)
• EPA Substance Registry System: Thiocyanic acid, (1Z)-3-oxo-1-phenyl-1-propenyl ester(49571-47-3)

Safety Data

• Hazardous Substances Data: 49571-47-3(Hazardous Substances Data)

Upstream product

• 33603-87-1 β-chlorocinnamaldehyde 
• 333-20-0 potassium thioacyanate 
• 33603-87-1 (Z)-3-chloro-3-phenyl-2-propenal 
• 2579-22-8 Phenylpropargyl aldehyde 

Downstream Products

• 18150-93-1 2-phenyl-5-nitrothiophene 

Relevant articles and documents

A stereoselective thiocyanate conjugate addition to electron deficient alkynes and concomitant cyclization to N,S-heterocycles

A regio- and stereoselective thiocyanate addition to ynones is achieved using KSCN in AcOH at 70 °C. The reaction is extendable to ynals, ynesulfones, ynoic acids and ynoates. Adducts from ynones were readily transformed into thiazine-2-thione derivatives under slightly modified reaction conditions. In contrast, thiocyanated adducts from ynamides underwent an in situ decyanative amido cyclization towards isothiazolones. None of these events needed any transition metal or catalyst, attaining a high synthetic value.