499783-28-7

Basic information

• Product Name: Carbamic acid, [(1S)-2-hydroxy-1-methyl-3-[(4-methylphenyl)thio]-3-nitropropyl]-, 1,1-dimethylethyl ester
• CAS NO: 499783-28-7
• Molecular Formula: C16H24N2O5S
• Molecular Weight: 356.443
• Mol File: 499783-28-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S)-2-hydroxy-1-methyl-3-[(4-methylphenyl)thio]-3-nitropropyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-2-hydroxy-1-methyl-3-[(4-methylphenyl)thio]-3-nitropropyl]-, 1,1-dimethylethyl ester(499783-28-7)
• EPA Substance Registry System: Carbamic acid, [(1S)-2-hydroxy-1-methyl-3-[(4-methylphenyl)thio]-3-nitropropyl]-, 1,1-dimethylethyl ester(499783-28-7)

Safety Data

• Hazardous Substances Data: 499783-28-7(Hazardous Substances Data)

Upstream product

• 28875-17-4 (S)-N-(tert-butoxycarbonyl)alanine methyl ester 
• 150640-22-5 <(4-methylphenyl)thio>nitromethane 
• 79069-50-4 Boc-Ala-H 

Downstream Products

• 499783-29-8 (Z)-(3S)-3-(tert-butoxycarbanylamino)-1-(4'-tolylthio)-1-nitrobut-1-ene 

Relevant articles and documents

Stereoselective synthesis of anti-β-amino-α-hydroxy acid derivatives using nucleophilic epoxidation of 1-arylthio-1-nitroalkenes

Reaction of lithium t-butylperoxide with 1-arylthio-1-nitroalkenes 5, prepared by condensation of (4-tolylthio)nitromethane with N-(Boc)-protected α-amino aldehydes, leads to the formation of oxazolidinones rather than the expected oxitranes. Initially, a mixture of cis 8 and trans 9 diastereoisomers is formed, but upon exposure to silica gel complete conversion to the cis-diastereoisomers 8 takes place.