500371-01-7

Basic information

• Product Name: 4H-Pyran-2-carboxaldehyde, 4-oxo-3-(phenylmethoxy)-
• Synonyms: 4H-Pyran-2-carboxaldehyde, 4-oxo-3-(phenylmethoxy)- ;3-(benzyloxy)-4-oxo-4H-pyran-2-carbaldehyde
• CAS NO: 500371-01-7
• Molecular Formula: C₁₃H₁₀O₄
• Molecular Weight: 230.2161
• Mol File: 500371-01-7.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 468.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.28±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 4H-Pyran-2-carboxaldehyde, 4-oxo-3-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Pyran-2-carboxaldehyde, 4-oxo-3-(phenylmethoxy)-(500371-01-7)
• EPA Substance Registry System: 4H-Pyran-2-carboxaldehyde, 4-oxo-3-(phenylmethoxy)-(500371-01-7)

Safety Data

• Hazardous Substances Data: 500371-01-7(Hazardous Substances Data)

Usage

General Description

4H-Pyran-2-carboxaldehyde, 4-oxo-3-(phenylmethoxy)- is a chemical compound consisting of a pyran ring with a carboxaldehyde group at the 2-position and a keto group at the 4-position, along with a phenylmethoxy substituent at the 3-position. 4H-Pyran-2-carboxaldehyde, 4-oxo-3-(phenylmethoxy)- has potential applications in organic synthesis and pharmaceutical research due to its structural and functional properties. It may be used as a building block for the synthesis of various organic molecules and pharmaceutical compounds, as well as in the development of new drugs and therapeutic agents. Additionally, it has the potential to exhibit biological activity and may be studied for its potential pharmacological effects. Overall, 4H-Pyran-2-carboxaldehyde, 4-oxo-3-(phenylmethoxy)- is a versatile and valuable chemical compound with diverse potential applications.

Upstream product

• 1206102-04-6 2-(2-hydroxy-2-phenylethyl)-3-[(phenylmethyl)oxy]-4H-pyran-4-one 
• 118-71-8 Maltol 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 1206102-05-7 2-[(E)-2-phenylethenyl]-3-[(phenylmethyl)oxy]-4H-pyran-4-one 
• 119736-15-1 2-(hydroxymethyl)-3-(phenylmethoxy)-4H-pyran-4-one 
• 61049-69-2 3-O-benzylmaltol 

Downstream Products

• 1315247-50-7 C₂₀H₁₈O₇ 
• 1402887-82-4 N,N',N''-(nitrilotris(ethane-2,1-diyl))tris(3-(benzyloxy)-4-oxo-1,4-dihydropyridine-2-carboxamide) 
• 1229006-25-0 methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-2-carboxylate 
• 1206102-11-5 (4R,12aS)-7-(benzyloxy)-N-(2,4-difluorobenzyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1′,2’:4,5]-pyrazino[2,1-b][1,3]oxazine-9-carboxamide 
• 1051375-16-6 dolutegravir 
• 1309561-95-2 C₁₈H₁₈N₂O₃ 
• 1309561-96-3 C₁₈H₁₇BrN₂O₃ 

Relevant articles and documents

Polycyclic pyridine oxime-based compound as well as pharmaceutical composition and application thereof

The invention discloses a polycyclic pyridine oxime-based compound and a pharmaceutical composition and application thereof, wherein the polycyclic pyridine oxime-based compound is shown as a formula (I). The compound shows strong inhibition of influenza

Spiro pyridone derivative and application

The invention discloses a spiro pyridone derivative which has a structure shown in a general formula I in the specification. Researches show that the spiro pyridinone derivative has a relatively strong inhibition effect on the activity of influenza A virus RNA polymerase, and can be applied to the preparation of influenza A virus RNA polymerase activity inhibition and influenza A resistance medicines. The general formula I is shown in the specification.

Purification and characterization of molybdenum-containing aldehyde dehydrogenase that oxidizes benzyl maltol derivative from Pseudomonas nitroreducens SB32154

Maltol derivatives are used in a variety of fields due to their metal-chelating abilities. In the previous study, it was found that cytochrome P450 monooxygenase, P450nov, which has the ability to effectively convert the 2-methyl group in a maltol derivative, transformed 3-benzyloxy-2-methyl-4-pyrone (BMAL) to 2-(hydroxymethyl)-3-(phenylmethoxy)-4H-pyran-4-one (BMAL-OH) and slightly to 3-benzyloxy-4-oxo-4 H-pyran-2-carboxaldehyde (BMAL-CHO). We isolated Pseudomonas nitroreducens SB32154 with the ability to convert BMAL-CHO to BMAL-COOH from soil. The enzyme responsible for aldehyde oxidation, a BMAL-CHO dehydrogenase, was purified from P. nitroreducens SB32154 and characterized. The purified BMAL-CHO dehydrogenase was found to be a xanthine oxidase family enzyme with unique structure of heterodimer composed of 75 and 15 kDa subunits containing a molybdenum cofactor and [Fe-S] clusters, respectively. The enzyme showed broad substrate specificity toward benzaldehyde derivatives. Furthermore, one-pot conversion of BMAL to BMAL-COOH via BMAL-CHO by the combination of the BMAL-CHO dehydrogenase with P450nov was achieved.