505065-18-9Relevant articles and documents
An iminodiacetate-modified conjugated polyelectrolyte for fluorescent labeling of histidine-tagged proteins
Cai, Kai,Tan, Ying,Tan, Chunyan,Wu, Jiatao,Wu, Pan,Liang, Jiamei,Liu, Shuwen,Zhang, Bibo,Jiang, Yuyang
, p. 4191 - 4194 (2017)
The iminodiacetate-Ni2+-hexahistidine system is extensively used in protein purification. In this study, an anionic conjugated polyelectrolyte (CPE) with a poly(p-phenylene ethynylene) backbone and iminodiacetate side chains, named PPEIDA, was designed and synthesized. Recognition and visualization of hexahistidine-tagged (His-tagged) proteins using PPEIDA was demonstrated.