507-60-8 Usage
Description
6-beta-acetoxy-3-beta(beta-D-glucopyranosyloxy)-8,14-dihydroxybufa-4,20,22-trienolide is a complex organic compound with a unique chemical structure. It is derived from the bufadienolides class of compounds, which are known for their potent cardiotonic and cytotoxic properties. This specific compound is characterized by the presence of a beta-acetoxy group at the 6-position, a beta-D-glucopyranosyloxy group at the 3-position, and hydroxyl groups at the 8 and 14 positions. 6-beta-acetoxy-3-beta(beta-D-glucopyranosyloxy)-8,14-dihydroxybufa-4,20,22-trienolide also features a bufa-4,20,22-trienolide backbone, which contributes to its biological activities.
Uses
Used in Pharmaceutical Industry:
6-beta-acetoxy-3-beta(beta-D-glucopyranosyloxy)-8,14-dihydroxybufa-4,20,22-trienolide is used as a pharmaceutical compound for its potent cardiotonic and cytotoxic effects. 6-beta-acetoxy-3-beta(beta-D-glucopyranosyloxy)-8,14-dihydroxybufa-4,20,22-trienolide's ability to modulate cellular processes and target specific receptors makes it a promising candidate for the development of new drugs to treat various cardiovascular and oncological conditions.
Used in Pest Control:
6-beta-acetoxy-3-beta(beta-D-glucopyranosyloxy)-8,14-dihydroxybufa-4,20,22-trienolide is used as a rodenticide in the pest control industry. 6-beta-acetoxy-3-beta(beta-D-glucopyranosyloxy)-8,14-dihydroxybufa-4,20,22-trienolide's cytotoxic properties make it effective in controlling rodent populations, particularly in situations where other methods have proven ineffective. However, its use in this application is subject to regulatory restrictions due to its potential risks to non-target species and the environment.
Used in Traditional Medicine:
6-beta-acetoxy-3-beta(beta-D-glucopyranosyloxy)-8,14-dihydroxybufa-4,20,22-trienolide has been used in traditional medicine for its various therapeutic properties. 6-beta-acetoxy-3-beta(beta-D-glucopyranosyloxy)-8,14-dihydroxybufa-4,20,22-trienolide's cardiotonic effects have been utilized in the treatment of heart failure, while its cytotoxic properties have been employed in the treatment of certain cancers. However, its use in traditional medicine should be approached with caution due to the potential for adverse effects and toxicity.
Toxicity evaluation
Red squill has a multitude of toxic effects. It is directly irritating
to the gastric mucosa, contributing to nausea, vomiting,
abdominal pain, diarrhea, and anorexia. Rats are not able to
vomit, contributing to the perceived selectivity of toxicity in
rats. Scilliroside and scillaren A are both cardiac glycosides,
and, like digoxin, inhibit Na+/K+ ATPase, block AV conduction,
and may cause a slowed or rapid heart rate and abnormal
heart rhythms.
Check Digit Verification of cas no
The CAS Registry Mumber 507-60-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,0 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 507-60:
(5*5)+(4*0)+(3*7)+(2*6)+(1*0)=58
58 % 10 = 8
So 507-60-8 is a valid CAS Registry Number.
InChI:InChI=1/C33H46O11/c1-17(35)42-22-14-32(4)24(9-11-31(3)20(8-12-33(31,32)40)18-5-6-25(36)41-16-18)30(2)10-7-19(13-21(22)30)43-29-28(39)27(38)26(37)23(15-34)44-29/h5-6,13,16,19-20,22-24,26-29,34,37-40H,7-12,14-15H2,1-4H3/t19-,20+,22+,23+,24+,26+,27-,28+,29+,30-,31+,32+,33+/m0/s1
