507-89-1 Usage
Description
PENNOGENIN, a natural product and a minor steroid component, is derived from Beth Root and is also found in the traditional Chinese medicine "Chonglou." It is a promising compound with potential applications in various industries due to its unique properties.
Uses
Used in Traditional Chinese Medicine:
PENNOGENIN is used as a medicinal component for its therapeutic properties in traditional Chinese medicine, particularly "Chonglou." It is valued for its potential health benefits and is an essential part of the formulation.
Used in Pharmaceutical Industry:
PENNOGENIN is used as a pharmaceutical compound for its potential applications in drug development. Its unique properties make it a candidate for further research and development, possibly leading to the creation of new medications.
Used in Natural Product Research:
PENNOGENIN is used as a subject of research in the field of natural products. Its presence in Beth Root and traditional Chinese medicine makes it an interesting compound to study for potential new applications and benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 507-89-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,0 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 507-89:
(5*5)+(4*0)+(3*7)+(2*8)+(1*9)=71
71 % 10 = 1
So 507-89-1 is a valid CAS Registry Number.
InChI:InChI=1/C27H42O4/c1-16-7-12-26(30-15-16)17(2)27(29)23(31-26)14-22-20-6-5-18-13-19(28)8-10-24(18,3)21(20)9-11-25(22,27)4/h5,16-17,19-23,28-29H,6-15H2,1-4H3/t16-,17-,19+,20-,21+,22+,23+,24+,25+,26-,27-/m1/s1
507-89-1Relevant articles and documents
Steroidal glycosides from the bulbs of Fritillaria meleagris and their cytotoxic activities
Matsuo, Yukiko,Shinoda, Daisuke,Nakamaru, Aina,Mimaki, Yoshihiro
, p. 670 - 682 (2013/07/05)
Steroidal glycosides (1-18), including 10 new compounds (1-10), were isolated from the bulbs of Fritillaria meleagris (Liliaceae). The structures of the new compounds were determined by two-dimensional (2D) NMR analysis, and by hydrolytic cleavage followed by spectroscopic and chromatographic analysis. The isolated compounds and their aglycones were evaluated for cytotoxic activity against HL-60 human promyelocytic leukemia cells and A549 human lung adenocarcinoma cells. Morphological observation and flow cytometry analysis showed that 5β-spirostanol glycoside (2) and a cholestane derivative (17a) induced apoptotic cell death in HL-60 cells through different mechanisms of action. Furthermore, the (22R)-spirosolanol glycoside (11) selectively induced apoptosis in A549 cells without affecting the caspase-3 activity level.
