509-80-8 Usage
Description
Mitraphyllin is a naturally occurring alkaloid compound found in the plant Mitragyna speciosa, which is native to Southeast Asia. It exhibits a range of pharmacological properties and has been the subject of various scientific studies due to its potential therapeutic applications.
Uses
Used in Pharmaceutical Research:
Mitraphyllin is used as a research compound for evaluating isoniazid resistance and antibiotic activity potentiation in Mycobacterium, a genus of bacteria that includes Mycobacterium tuberculosis, the causative agent of tuberculosis. This application is crucial for developing new strategies to combat drug-resistant strains of Mycobacterium and improving the efficacy of existing antibiotic treatments.
Additionally, Mitraphyllin may have potential applications in other areas of pharmaceutical research, such as the development of new drugs for various diseases, based on its unique chemical structure and biological activities. However, further studies are needed to fully understand its potential and safety profile before it can be used in clinical settings.
Check Digit Verification of cas no
The CAS Registry Mumber 509-80-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,0 and 9 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 509-80:
(5*5)+(4*0)+(3*9)+(2*8)+(1*0)=68
68 % 10 = 8
So 509-80-8 is a valid CAS Registry Number.
509-80-8Relevant articles and documents
Analysis of the kinetics of isomerization of spiro oxindole alkaloids
Laus, Gerhard,Broessner, Dagmar,Senn, Gilbert,Wurst, Klaus
, p. 1931 - 1936 (2007/10/03)
The isomerization of the spiro oxindole alkaloids mitraphylline, isomitraphylline, pteropodine, isopteropodine, speciophylline and uncarine F in water has been studied at several temperatures and the rate coefficients have been determined. The effect of pH on the rate of reaction and the equilibrium composition has been investigated. The rate coefficients in water and in organic solvents correlate satisfactorily with the Dimroth-Reichardt solvent polarity parameter. The present results support the existence of a zwitterionic intermediate stabilized by polar solvents and show that protonation of the alkaloids inhibits the isomerization. The crystal structure of pteropodine has been determined.
Yohimbane derivatives. 3. The oxidative rearrangement of indole alkaloids to their spirooxindole analogs.
Zinnes,Shavel Jr.
, p. 1765 - 1771 (2007/11/06)
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