5098-99-7

Basic information

• Product Name: (4Z)-4-[(4-methylphenyl)hydrazono]naphthalen-1(4H)-one
• CAS NO: 5098-99-7
• Molecular Formula: C₁₇H₁₄N₂O
• Molecular Weight: 262.3059
• Mol File: 5098-99-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 418.4°C at 760 mmHg
• Flash Point: 206.8°C
• Density: 1.15g/cm³
• Vapor Pressure: 3.3E-07mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: (4Z)-4-[(4-methylphenyl)hydrazono]naphthalen-1(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4Z)-4-[(4-methylphenyl)hydrazono]naphthalen-1(4H)-one(5098-99-7)
• EPA Substance Registry System: (4Z)-4-[(4-methylphenyl)hydrazono]naphthalen-1(4H)-one(5098-99-7)

Safety Data

• Hazardous Substances Data: 5098-99-7(Hazardous Substances Data)

Usage

Description

(4Z)-4-[(4-methylphenyl)hydrazono]naphthalen-1(4H)-one, a hydrazine derivative with a naphthalene core structure, is a chemical compound characterized by the molecular formula C17H14N2O. Its unique chemical structure and properties render it a versatile and useful compound in various scientific and industrial applications.

Uses

Used in Organic Synthesis:
(4Z)-4-[(4-methylphenyl)hydrazono]naphthalen-1(4H)-one is utilized as a reagent in organic synthesis, playing a crucial role in the formation of various organic compounds. Its ability to participate in a range of chemical reactions makes it a valuable asset in this field.
Used in Medicinal Chemistry:
Possessing potential applications in medicinal chemistry, (4Z)-4-[(4-methylphenyl)hydrazono]naphthalen-1(4H)-one can be employed as a building block for the development of new pharmaceuticals. Its unique structure may contribute to the creation of novel drugs with improved efficacy and selectivity.
Used as a Dye Precursor:
In the chemical industry, (4Z)-4-[(4-methylphenyl)hydrazono]naphthalen-1(4H)-one serves as a precursor for the synthesis of dyes. Its chemical properties allow for the production of a variety of dye compounds, contributing to the diversity of colors available for various applications.
Used in Research and Development:
(4Z)-4-[(4-methylphenyl)hydrazono]naphthalen-1(4H)-one's unique structure and reactivity make it an essential tool in research and development, particularly in the fields of chemistry and materials science. It can be used to study reaction mechanisms, develop new synthetic methods, and explore novel applications in various industries.

Upstream product

• 36853-51-7 Naphthochinon-(1,4)-yl-<4-methyl-phenylhydrazon> 
• 90-15-3 α-naphthol 
• 106-49-0 p-toluidine 
• 57573-52-1 4-methylbenzene diazonium 
• 637-60-5 p-tolylhydrazine hydrochloride 
• 130-15-4 [1,4]naphthoquinone 
• 2028-84-4 p-methylbenzenediazonium chloride 

Downstream Products

• 71811-76-2 (4-methoxy-[1]naphthyl)-p-tolyl-diazene 
• 605-69-6 1-hydroxy-2,4-dinitronaphthalene 
• 36853-51-7 Naphthochinon-(1,4)-yl-<4-methyl-phenylhydrazon> 
• 108-88-3 toluene 
• 130-15-4 [1,4]naphthoquinone 

Relevant articles and documents

Diaryl azo derivatives as anti-diabetic and antimicrobial agents: synthesis, in vitro, kinetic and docking studies

In the present study, a series of azo derivatives (TR-1 to TR-9) have been synthesised via the diazo-coupling approach between substituted aromatic amines with phenol or naphthol derivatives. The compounds were evaluated for their therapeutic applications against alpha-glucosidase (anti-diabetic) and pathogenic bacterial strains E. coli (gram-negative), S. aureus (gram-positive), S. aureus (gram-positive) drug-resistant strain, P. aeruginosa (gram-negative), P. aeruginosa (gram-negative) drug-resistant strain and P. vulgaris (gram-negative). The IC50 (μg/mL) of TR-1 was found to be most effective (15.70 ± 1.3 μg/mL) compared to the reference drug acarbose (21.59 ± 1.5 μg/mL), hence, it was further selected for the kinetic studies in order to illustrate the mechanism of inhibition. The enzyme inhibitory kinetics and mode of binding for the most active inhibitor (TR-1) was performed which showed that the compound is a non-competitive inhibitor and effectively inhibits the target enzyme by binding to its binuclear active site reversibly.

Facile synthesis of 1-naphthol azo dyes with nano Sio2/Hio4 under solvent-free conditions

Nano-silica supported periodic acid (nano-SPIA) has been utilized as a heterogeneous reagent for a highly efficient and one pot synthesis of azo dyes based on 1-naphthol under solvent-free conditions at room temperature. This method has some advantages, the reaction workup is very easy and the catalyst can be easily separated from the reaction mixture and one-pot procedure. The related products have been obtained in good to excellent yields, high purity and short reaction times. The structures of the products have been characterized by several techniques using UV-Vis, FT-IR, 1H NMR, 13C NMR and mass spectra.

Solid state photolysis of triazene 1-oxides with naphthols. Synthesis of azo dyes

Sunlight irradiation of solid mixed crystals of the photolabile triazene 1-oxides and α- or β-naphthol afford azo dyes.