51052-74-5

Basic information

• Product Name: 3-hydroxy-1,1-dimethyl pyrrolidinium bromide
• CAS NO: 51052-74-5
• Molecular Weight: 196.087
• Mol File: 51052-74-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-1,1-dimethyl pyrrolidinium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-1,1-dimethyl pyrrolidinium bromide(51052-74-5)
• EPA Substance Registry System: 3-hydroxy-1,1-dimethyl pyrrolidinium bromide(51052-74-5)

Safety Data

• Hazardous Substances Data: 51052-74-5(Hazardous Substances Data)

Usage

Uses

1,1-Dimethyl-3-hydroxypyrrolidinium Bromide is a metabolite found in the kidney and liver in response to oral administration of glycopyrrolate.

Upstream product

• 596-51-0 glycopyrronium bromide 

Relevant articles and documents

GLYCOPYRRONIUM FATTY ACID SALTS AND METHODS OF MAKING SAME

Novel glycopyrronium fatty acid salts have been developed. Bi-phasic reaction conditions enable the desired counterion exchange reactions between glycopyrronium bromide and fatty acid salts of alkali metals and alkaline earth metals in methods to form glycopyrronium fatty acid salts. In preferred embodiments, an excess of the free fatty acid in the reaction mixture stabilizes the glycopyrronium fatty acid salt and reduces the formation of the impurity, Acid A. In some preferred embodiments, between 0.2 and 1.2 molar equivalent of excess free fatty acid is added to the reaction mixture. In another embodiment, approximately 1.2 molar equivalent of excess free fatty acid is added to the reaction mixture.