51072-64-1

Basic information

• Product Name: 2-BROMO-4,5-DIMETHOXY-BENZENESULFONYL CHLORIDE
• Synonyms: 2-BROMO-4,5-DIMETHOXY-BENZENESULFONYL CHLORIDE;2-Bromo-4,5-dimethoxybenzenesulponyl chloride;2-Bromo-4,5-dimethoxysulfonyl chloride;2-BROMO-4,5-DIMETHOXYBENZENE-1-SULFONYL CHLORIDE
• CAS NO: 51072-64-1
• Molecular Formula: C₈H₈BrClO₄S
• Molecular Weight: 315.57
• Mol File: 51072-64-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 391.3°C at 760 mmHg
• Flash Point: 190.5°C
• Appearance: /
• Density: 1.658g/cm³
• Vapor Pressure: 5.61E-06mmHg at 25°C
• Refractive Index: 1.552
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-BROMO-4,5-DIMETHOXY-BENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4,5-DIMETHOXY-BENZENESULFONYL CHLORIDE(51072-64-1)
• EPA Substance Registry System: 2-BROMO-4,5-DIMETHOXY-BENZENESULFONYL CHLORIDE(51072-64-1)

Safety Data

• Hazardous Substances Data: 51072-64-1(Hazardous Substances Data)

Usage

General Description

2-Bromo-4,5-dimethoxy-benzenesulfonyl chloride is a chemical compound that is used in the synthesis of pharmaceuticals and agrochemicals. It is an important intermediate in the preparation of various biologically active compounds and is often used as a reagent in organic synthesis. 2-BROMO-4,5-DIMETHOXY-BENZENESULFONYL CHLORIDE is a sulfonating agent and is commonly used to introduce the sulfonyl chloride functional group into organic molecules. It is a versatile building block for the preparation of various complex organic compounds and is widely used in the pharmaceutical and agrochemical industries.

InChI:InChI=1/C8H8BrClO4S/c1-13-6-3-5(9)8(15(10,11)12)4-7(6)14-2/h3-4H,1-2H3

Upstream product

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Relevant articles and documents

Nickel-Catalyzed One-Pot Carbonylative Synthesis of 2-Mono- And 2,3-Disubstituted Thiochromenones from 2-Bromobenzenesulfonyl Chlorides and Alkynes

A nickel-catalyzed one-pot carbonylation reaction of 2-bromobenzenesulfonyl chlorides with alkynes for the synthesis of thiochromenones has been established. Both terminal and internal alkynes were suitable substrates in this carbonylative transformation, and a broad range of 2-mono- and 2,3-disubstituted thiochromenone products were obtained in moderate to good yields with quite high functional group compatibility. Notably, this procedure presents the first example of nickel-catalyzed carbonylative synthesis of thiochromenones with 2-bromobenzenesulfonyl chlorides as a promising sulfur precursor.

Halonium ion triggered rearrangement of unsaturated benzo-annulated bi- and tricyclic sulfonamides

The halonium ion mediated 1,2-Wagner-Meerwein-type rearrangement of a series of benzo-fused bi- and tricyclic sulfonamides is reported. During this rearrangement the carbon-carbon bond that migrates was selectively set in the intramolecular Mizoroki-Heck

Urotensin-II receptor antagonists

P51084 The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.